Early haemorrhage control and minimizing the time to definitive care have long been the
cornerstones of therapy for patients exsanguinating from non-compressible haemorrhage …

Background Trauma-related injury causes higher mortality than a combination of prevalent
infectious diseases. Mortality secondary to trauma is higher in low-and middle-income …

Objective Cardiovascular disease is the leading cause of death worldwide, responsible for
17.5 million deaths every year, of which 80% occur in low-and middle-income countries …

Background: Recent studies have suggested improved outcomes in victims of penetrating
trauma managed with shorter prehospital times and limited interventions. The purpose of the …

The Trauma Care Manual 3e is the definitive evidence-based manual of best trauma
practice. Now in its third edition, this valuable book continues to provide clear practical …

Tissue injury and hemorrhage induced by trauma lead to degradation of the endothelial
glycocalyx, causing syndecan-1 (SDC-1) to be shed into the blood. In this study, we …

Physical trauma is one of the leading causes of mortality worldwide. Early post-traumatic
upregulation of the pro-inflammatory immune response to traumatic injury is paralleled by an …

Multiple injuries appear to be a decisive factor for experimental polytrauma. Therefore, our
aim was to compare the inflammatory response and organ damage of five different …

Background Though road traffic injuries (RTIs) are a major cause of mortality in East Africa,
few countries have emergency medical services. The aim was to create a sustainable and …

Background: Tension pneumothorax (TPT) is a frequent life-threat following thoracic injury.
Time-critical decompression of the pleural cavity improves survival. However, whilst …