[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis

S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …

Advances in the utilization of zebrafish for assessing and understanding the mechanisms of nano-/microparticles toxicity in water

P Lei, W Zhang, J Ma, Y Xia, H Yu, J Du, Y Fang… - Toxics, 2023 - mdpi.com
A large amount of nano-/microparticles (MNPs) are released into water, not only causing
severe water pollution, but also negatively affecting organisms. Therefore, it is crucial to …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

Swimming against ALS: How to model disease in zebrafish for pathophysiological and behavioral studies

NAS Oliveira, BR Pinho, JMA Oliveira - Neuroscience & Biobehavioral …, 2023 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that leads to
progressive disability and motor impairment. Existing therapies provide modest …

Experimental models of chemically induced Parkinson's disease in zebrafish at the embryonic larval stage: a systematic review

P Briñez-Gallego, DG da Costa Silva… - Journal of Toxicology …, 2023 - Taylor & Francis
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the substantia nigra that results in a decrease in dopamine levels …

Coupling of sharp wave events between zebrafish hippocampal and amygdala homologs

I Blanco, A Caccavano, JY Wu, S Vicini… - Journal of …, 2024 - Soc Neuroscience
The mammalian hippocampus exhibits spontaneous sharp wave events (1–30 Hz) with an
often-present superimposed fast ripple oscillation (120–220 Hz) to form a sharp wave ripple …

Assessing drug administration techniques in zebrafish models of neurological disease

V Chaoul, EY Dib, J Bedran, C Khoury… - International Journal of …, 2023 - mdpi.com
Neurological diseases, including neurodegenerative and neurodevelopmental disorders,
affect nearly one in six of the world's population. The burden of the resulting deaths and …

A novel fluorescent probe with tailored properties for ozone: Applications in on-site environmental monitoring and real-time bioimaging in Parkinson's disease models

L Li, X Zhao, Y Tian, J Li, Z Yang, X Liu, Y Li… - Sensors and Actuators B …, 2024 - Elsevier
Ozone (O 3) is not only a widespread environmental contaminant at the troposphere or
ground level, but also a significant reactive oxygen species (ROS) in vivo that participates in …

Towards zebrafish models of CNS channelopathies

TO Kolesnikova, KA Demin, FV Costa… - International Journal of …, 2022 - mdpi.com
Channelopathies are a large group of systemic disorders whose pathogenesis is associated
with dysfunctional ion channels. Aberrant transmembrane transport of K+, Na+, Ca2+ and …

Fish Models for Exploring Mitochondrial Dysfunction Affecting Neurodegenerative Disorders

T Otsuka, H Matsui - International Journal of Molecular Sciences, 2023 - mdpi.com
Neurodegenerative disorders are characterized by the progressive loss of neuronal
structure or function, resulting in memory loss and movement disorders. Although the …