Comprehensive Coverage on Anti‐mycobacterial Endeavour Reported in 2021

TM Dhameliya, AA Devani, KA Patel… - ChemistrySelect, 2022 - Wiley Online Library
Tuberculosis (TB) has been the highly contagious airborne disease caused by
Mycobacterium tuberculosis and the major leading infectious disease with the higher …

Design and synthesis of novel benzimidazole linked thiazole derivatives as promising inhibitors of drug-resistant tuberculosis

K Veena, MS Raghu, KY Kumar, CBP Kumar… - Journal of Molecular …, 2022 - Elsevier
Despite combination therapy is effective in treating tuberculosis (TB) caused by susceptible
Mycobacterium tuberculosis (Mtb) strains, overcoming multidrug resistance (MDR) remains …

Novel 2-arylthiazolidin-4-one-thiazole hybrids with potent activity against Mycobacterium tuberculosis

DIA Othman, A Hamdi, MM Abdel-Aziz, SM Elfeky - Bioorganic Chemistry, 2022 - Elsevier
Abstract Substituted aldehydes, ethyl 2-(2-amino-thiazol-4-yl) acetate), and 2-
mercaptoacetic acid, in a three-component one-pot green synthetic approach afforded 2 …

Click synthesis, anticancer activity, and molecular docking investigation of some functional 1, 2, 3-triazole derivatives

M Hrimla, A Oubella, MR Laamari, L Bahsis… - … Research in Applied …, 2022 - rodrigo.uv.es
1, 2, 3-triazole skeleton is a privileged building block for the discovery of new promising
anticancer agents. In this report, new 1, 4-disubstituted 1, 2, 3-triazoles with the bioisoster …

Spectroscopic characterization, molecular docking, and in vitro antibacterial activity of 4-(methyl sulfonyl) benzaldehyde: A DFT approach

RM Cherian, V Vinod, SM John, V Suresh… - Journal of Molecular …, 2024 - Elsevier
Abstract FT-IR, FT-Raman and UV–Vis spectra of antibacterial interest compound 4-(methyl
sulfonyl) benzaldehyde (MSB) have been recorded and analyzed both theoretical as well as …

Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities

R Keleş Atıcı, ŞD Doğan, MG Gündüz… - Drug Development …, 2022 - Wiley Online Library
The recent emergence of drug‐resistant strains of Mycobacterium tuberculosis (Mtb) has
complicated and significantly slowed efforts to eradicate and/or reduce the worldwide …

Synthesis, characterization of Ru (III) macrocyclic complex with hirshfeld analysis and drug likeness study

R Kanaoujiya, DK Sahu, V Shankar… - Materials Today …, 2022 - Elsevier
In this study noble macrocyclic ligand complexes of Ru (III) have been synthesized with
macrocyclic ligand such as 1, 4, 8, 11-tetraazacyclotetradecane and evaluated for the …

Analysis of biological properties of 1, 2, 4-triazole-containing compounds (literature review)

AV Khilkovets, VV Parchenko - 2022 - dspace.zsmu.edu.ua
Conclusions. Among these derivatives, molecules that exhibit broad antifungal and
antimicrobial activity, antitubercular, antiviral, actoprotective, antihypoxic, analgesic effects …

[HTML][HTML] Photoprotective Effects of Two New Morin-Schiff Base Derivatives on UVB-Irradiated HaCaT Cells

S García-Gil, A Rodríguez-Luna, J Ávila-Román… - Antioxidants, 2024 - mdpi.com
Ultraviolet (UV) radiation harms the skin, causing oxidative damage, inflammation, and
disruption of the skin's barrier function. There is considerable interest in identifying new …

Synthesis, type II diabetes inhibitory activity and docking studies of novel thiazole molecules

JI Jadeja, MM Savant - Journal of Chemical Sciences, 2023 - Springer
A series of novel ethyl (E)-2-cyano-3-((4-methyl-5-(arylcarbamoyl) thiazol-2-yl) amino)-3-
(methylthio) acrylate have been synthesized starting from various 2-amino-N-aryl-4 …