Purpose Shared decision making manages genomic uncertainty by integrating molecular
and clinical uncertainties with patient values to craft a person-centered management plan …

Polygenic risk scores (PRSs) enable early prediction of disease risk. Evaluating PRS
performance for binary traits commonly relies on the area under the receiver operating …

We present evidence from diverse disciplines and populations to identify the current and
emerging role of genomics in prevention from both medical and public health perspectives …

(1) Background: Genomic precision medicine (PM) utilises people's genomic data to inform
the delivery of preventive and therapeutic health care. PM has not been well-established for …

Prostate cancer is a dominant global threat to society. It affects nearly 4000 men in South
Africa annually, making it the second most threatening cancerous disease after lung cancer …

Objetivo Describir críticamente la respuesta en investigación e innovación (I+ I) contra la
sindemia por COVID-19 en el ámbito nacional, contextualizada internacionalmente. Método …

В статье дана попытка обоснования необходимости уголовно-правовой охраны
генетического достоинства. В последние годы, ставшие поистине «прорывными» в …

Next-generation sequencing (NGS) technology has revamped the area of genetics with
improve the sequence of a substantial number of genes with high accuracy and short turn …

Hyperphenylalaninemia (HPA), the most common amino acid metabolism disorder, is
caused by defects in enzymes involved in phenylalanine metabolism, with the consequent …

В современной медицине все большее значение приобретают персонализированные
подходы к диагностике, профилактике и лечению заболеваний. Накопленная …