Background GJB2 plays an essential role in the growth and progression of several cancers.
However, asystematic pan-cancer analysis of GJB2 is lacking. Therefore, in this study, we …

Ion channels, transporters, and other ion-flux controlling proteins, collectively comprising the
“ion permeome”, are common drug targets, however, their roles in cancer remain …

Stromal fibrosis in cancer is usually associated with poor prognosis and chemotherapy
resistance. It is thought to be caused by fibroblasts; however, the exact mechanism is not yet …

Deafness is a common sensory disorder. In China, approximately 70% of hereditary
deafness originates from four common deafness-causing genes: GJB2, SLC26A4, GJB3 …

PDE1B had been found to be involved in various diseases, including tumors and non-
tumors. However, little was known about the definite role of PDE1B in osteosarcoma …

RhoB, a member of the Rho GTPase family, has been implicated in the malignant
progression of various cancer types. However, its role in cervical cancer (CC) remains …

Ion channels, transporters, and other ion-permeating proteins, collectively comprising the
ion permeome (IP), are common drug targets. However, their roles in cancer are …

The protein family of copper metabolism MURR1 domain-containing (COMMD) is highly
conserved in eukaryotic multicellular organisms and participates in numerous cellular …

Ion channels, transporters, and other ion-flux controlling proteins, collectively comprising the
“ion permeome”, are common drug targets, however, their roles in cancer remain …