Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
K Le Blanc, L Tammik, B Sundberg… - Scandinavian …, 2003 - Wiley Online Library
We aimed to study the effects of mesenchymal stem cells (MSCs) on alloreactivity and
effects of T‐cell activation on human peripheral blood lymphocytes (PBLs) in vitro. MSCs …
effects of T‐cell activation on human peripheral blood lymphocytes (PBLs) in vitro. MSCs …
[HTML][HTML] Mesenchymal stem cells: biology and potential clinical uses
RJ Deans, AB Moseley - Experimental hematology, 2000 - Elsevier
There has been an increasing interest in recent years in the stromal cell system functioning
in the support of hematopoiesis. The stromal cell system has been proposed to consist of …
in the support of hematopoiesis. The stromal cell system has been proposed to consist of …
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone
H Zhu, ZK Guo, XX Jiang, H Li, XY Wang, HY Yao… - Nature protocols, 2010 - nature.com
Unlike humans, mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be
easily harvested by adherence to plastic owing to the contamination of cultures by …
easily harvested by adherence to plastic owing to the contamination of cultures by …
Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche
RS Taichman - Blood, 2005 - ashpublications.org
The mechanisms of bone and blood formation have traditionally been viewed as distinct,
unrelated processes, but compelling evidence suggests that they are intertwined. Based on …
unrelated processes, but compelling evidence suggests that they are intertwined. Based on …
[HTML][HTML] Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
JP Lévesque, J Hendy, Y Takamatsu… - The Journal of …, 2003 - Am Soc Clin Investig
Hematopoietic progenitor cells (HPCs) normally reside in the bone marrow (BM) but can be
mobilized into the peripheral blood (PB) after treatment with GCSF or chemotherapy. In …
mobilized into the peripheral blood (PB) after treatment with GCSF or chemotherapy. In …
The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34+ cells: role in transendothelial/stromal migration and engraftment …
A Peled, O Kollet, T Ponomaryov, I Petit… - Blood, The Journal …, 2000 - ashpublications.org
Hematopoietic stem cell homing and engraftment require several adhesion interactions,
which are not fully understood. Engraftment of nonobese/severe combined …
which are not fully understood. Engraftment of nonobese/severe combined …
Mesenchymal stem cells: characteristics and clinical applications.
S Bobis, D Jarocha, M Majka - Folia histochemica et …, 2006 - journals.viamedica.pl
Mesenchymal stem cells (MSCs) are bone marrow populating cells, different from
hematopoietic stem cells, which possess an extensive proliferative potential and ability to …
hematopoietic stem cells, which possess an extensive proliferative potential and ability to …
Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal …
M Majka, A Janowska-Wieczorek… - Blood, The Journal …, 2001 - ashpublications.org
The aim of this study was to explore further the hypothesis that early stages of normal human
hematopoiesis might be coregulated by autocrine/paracrine regulatory loops and by cross …
hematopoiesis might be coregulated by autocrine/paracrine regulatory loops and by cross …
Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
The chemokine, stromal cell–derived factor-1 (SDF1), is produced in the bone marrow and
has been shown to modulate the homing of stem cells to this site by mediating chemokinesis …
has been shown to modulate the homing of stem cells to this site by mediating chemokinesis …
Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte …
JP Lévesque, Y Takamatsu, SK Nilsson… - Blood, The Journal …, 2001 - ashpublications.org
Mobilized progenitor cells currently represent the most commonly used source of
hematopoietic progenitor cells (HPCs) to effect hematopoietic reconstitution following …
hematopoietic progenitor cells (HPCs) to effect hematopoietic reconstitution following …