[HTML][HTML] Mitochondrial electron transport chain, ROS generation and uncoupling
RZ Zhao, S Jiang, L Zhang… - … journal of molecular …, 2019 - spandidos-publications.com
The mammalian mitochondrial electron transport chain (ETC) includes complexes I‑IV, as
well as the electron transporters ubiquinone and cytochrome c. There are two electron …
well as the electron transporters ubiquinone and cytochrome c. There are two electron …
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
MD Brand - Free Radical Biology and Medicine, 2016 - Elsevier
This review examines the generation of reactive oxygen species by mammalian
mitochondria, and the status of different sites of production in redox signaling and pathology …
mitochondria, and the status of different sites of production in redox signaling and pathology …
[HTML][HTML] SARS-CoV-2 mediated endothelial dysfunction: the potential role of chronic oxidative stress
Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity
Obesity is accompanied by numerous systemic and tissue-specific derangements, including
systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal …
systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal …
[HTML][HTML] Bacterial pigments: sustainable compounds with market potential for pharma and food industry
The continued universal application of synthetic colorants for decades have caused
environmental pollutions and human health vulnerabilities. So, it was indispensable to …
environmental pollutions and human health vulnerabilities. So, it was indispensable to …
[HTML][HTML] Mitochondrial dysfunction: the hidden player in the pathogenesis of atherosclerosis?
G Ciccarelli, S Conte, G Cimmino, P Maiorano… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of …
B Szczesny, K Módis, K Yanagi, C Coletta… - Nitric oxide, 2014 - Elsevier
The purpose of the current study was to investigate the effect of the recently synthesized
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …
Inflammation and atherosclerosis—revisited
S Pant, A Deshmukh, GS GuruMurthy… - Journal of …, 2014 - journals.sagepub.com
Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …
Riding the tiger–physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix
MD Brand - Critical Reviews in Biochemistry and Molecular Biology, 2020 - Taylor & Francis
Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …
wide range of physiological responses and pathologies. Concentrations of superoxide and …
[HTML][HTML] Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties
For their various bioactivities, biomaterials derived from marine algae are important
ingredients in many products, such as cosmetics and drugs for treating cancer and other …
ingredients in many products, such as cosmetics and drugs for treating cancer and other …