[HTML][HTML] Chemical composition, antioxidant, anti-inflammatory and cytotoxic effects of Chondrus crispus species of red algae collected from the Red Sea along the …

MI Alkhalaf - Journal of King Saud University-Science, 2021 - Elsevier
Abstract The Red Sea coast is rich in different types of seaweeds, which are suggested to
possess medicinal properties. In this study, methanolic extract of Chondrus crispus (MEC), a …

[HTML][HTML] The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission

M Huang, R Wei, Y Wang, T Su, P Li, X Chen - Redox biology, 2018 - Elsevier
The accumulation of uremic toxins in chronic kidney disease (CKD) induces inflammation,
oxidative stress and endothelial dysfunction, which is a key step in atherosclerosis …

Childhood obesity: immune response and nutritional approaches

T Magrone, E Jirillo - Frontiers in immunology, 2015 - frontiersin.org
Childhood obesity is characterized by a low-grade inflammation status depending on the
multicellular release of cytokines, adipokines, and reactive oxygen species. In particular, the …

Association between ferritin and hepcidin levels and inflammatory status in patients with type 2 diabetes mellitus and obesity

M Andrews, N Soto, M Arredondo-Olguín - Nutrition, 2015 - Elsevier
Objective The aim of this study was to determine the association between iron parameters
and inflammation in obese individuals with and without type 2 diabetes mellitus (T2DM) …

Mitochondrial DAMPs and altered mitochondrial dynamics in OxLDL burden in atherosclerosis

B Khwaja, FG Thankam, DK Agrawal - Molecular and Cellular …, 2021 - Springer
Atherosclerosis results in life-threatening cardiovascular pathologies, including ischemic
heart disease, stroke, myocardial infarction, and peripheral arterial disease. The role of …

MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle …

T Pham, CL MacRae, SC Broome, RF D'souza… - European Journal of …, 2020 - Springer
Purpose Excess production of reactive oxygen species (ROS) from the mitochondria can
promote mitochondrial dysfunction and has been implicated in the development of a range …

Mitochondrial aldehyde dehydrogenase activation by Alda‐1 inhibits atherosclerosis and attenuates hepatic steatosis in apolipoprotein E‐knockout mice

A Stachowicz, R Olszanecki, M Suski… - Journal of the …, 2014 - Am Heart Assoc
Background Mitochondrial dysfunction has been shown to play an important role in the
development of atherosclerosis and nonalcoholic fatty liver disease (NAFLD). Mitochondrial …

Impaired mitophagy induces antimicrobial responses in macrophages infected with Mycobacterium tuberculosis

J Lee, SA Lee, SH Son, JA Choi, TD Nguyen, J Kim… - Cell & Bioscience, 2023 - Springer
Background Mitophagy, mitochondrial selective autophagy, plays a pivotal role in the
maintenance of cellular homeostasis in response to cellular stress. However, the role of …

The antiradical activity of some selected flavones and flavonols. Experimental and quantum mechanical study

Z Sroka, B Żbikowska, J Hładyszowski - Journal of molecular modeling, 2015 - Springer
The aim of the study was to examine the antiradical and antioxidant activity of some flavones
and flavonols with different models of hydroxylation and methoxylation. Antiradical activity …

Beneficial effects of ursolic acid and its derivatives—focus on potential biochemical mechanisms in cardiovascular conditions

J Erdmann, M Kujaciński, M Wiciński - Nutrients, 2021 - mdpi.com
Ursolic acid (UA) is a natural pentacyclic triterpenoid found in a number of plants such as
apples, thyme, oregano, hawthorn and others. Several in vitro and in vivo studies have …