SIRT6 in regulation of mitochondrial damage and associated cardiac dysfunctions: a possible therapeutic target for CVDs

KP Divya, N Kanwar, PV Anuranjana, G Kumar… - Cardiovascular …, 2024 - Springer
Cardiovascular diseases (CVDs) can be described as a global health emergency imploring
possible prevention strategies. Although the pathogenesis of CVDs has been extensively …

Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause

FF Conti, J de Oliveira Brito, N Bernardes… - BMC cardiovascular …, 2014 - Springer
Background Metabolic syndrome is characterized by the association of 3 or more risk
factors, including: abdominal obesity associated with an excess of abdominal fat, insulin …

Acetyl-L-carnitine and Amyotrophic Lateral Sclerosis: Current evidence and potential use

F De Marchi, S Venkatesan, M Saraceno… - CNS & Neurological …, 2024 - ingentaconnect.com
Background: The management of neurodegenerative diseases can be frustrating for
clinicians, given the limited progress of conventional medicine in this context. Aim: For this …

Idebenone protects against oxidized low density lipoprotein induced mitochondrial dysfunction in vascular endothelial cells via GSK3β/β-catenin signalling pathways

P Lin, J Liu, M Ren, K Ji, L Li, B Zhang, Y Gong… - Biochemical and …, 2015 - Elsevier
The early stages of the atherosclerotic process are initiated by accumulation of oxidized low-
density lipoprotein (oxLDL) and damage to the structure or function of the endothelium …

Baru almonds increase the activity of glutathione peroxidase in overweight and obese women: A randomized, placebo-controlled trial

RGM de Souza, AC Gomes, AM Navarro, LC Cunha… - Nutrients, 2019 - mdpi.com
Background: Obesity-induced inflammation is frequently associated with higher oxidative
stress. In vitro and experimental studies have considered baru almonds (Dipteryx alata Vog) …

Increased susceptibility to amyloid-β toxicity in rat brain microvascular endothelial cells under hyperglycemic conditions

C Carvalho, PS Katz, S Dutta… - Journal of …, 2014 - content.iospress.com
We hypothesized that hyperglycemia-induced mitochondrial dysfunction and oxidative
stress are closely associated with amyloid-ß peptide (Aß) toxicity in endothelial cells. Brain …

[HTML][HTML] Potential antioxidant and cytoprotective effects of essential oil extracted from Cymbopogon citratus on OxLDL and H2O2 LDL induced Human Peripheral …

S Jamuna, S Sadullah, R Ashokkumar… - Food Science and …, 2017 - Elsevier
Cymbopogon citratus (lemon grass) is commonly used in traditional folk medicine. The
essential oil extracted from C. citratus has been reported as a potential anti-oxidant and anti …

n-3 fatty acids modulate adipose tissue inflammation and oxidative stress

C Fan, H Zirpoli, K Qi - Current Opinion in Clinical Nutrition & …, 2013 - journals.lww.com
n-3 fatty acids modulate adipose tissue inflammation and oxi... : Current Opinion in Clinical
Nutrition & Metabolic Care n-3 fatty acids modulate adipose tissue inflammation and oxidative …

Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice

HT Wang, CF Liu, TH Tsai, YL Chen, HW Chang… - Journal of translational …, 2012 - Springer
Background Obesity is an important cardiovascular risk factor. This study tested the effect of
obesity reduction on preserving left ventricular ejection fraction (LVEF) and attenuating …

Cardiovascular toxicities of small molecule tyrosine kinase inhibitors: an opportunity for systems‐based approaches

SA Brown, L Nhola, J Herrmann - Clinical Pharmacology & …, 2017 - Wiley Online Library
Once universally considered a rapidly fatal condition, cancer has increasingly become a
chronic medical condition and comorbidities and adverse effects of cancer therapies have …