Sleep plays an important role in maintaining neuronal circuitry, signalling and helps
maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian …

Alzheimer's disease (AD) is the most common type of dementia and typically manifests
through a progressive loss of episodic memory and cognitive function, subsequently causing …

The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …

Microglia are the predominant immune cells of the central nervous system (CNS) that exert
key physiological roles required for maintaining CNS homeostasis, notably in response to …

Stress is viewed as a state of real or perceived threat to homeostasis, the management of
which involves the endocrine, nervous, and immune systems. These systems work …

Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Tauopathies, including Alzheimer's disease (AD) and frontotemporal lobar degeneration
with tau pathologies, are neurodegenerative diseases characterized by neurofibrillary …

Importance The use of anticholinergic (AC) medication is linked to cognitive impairment and
an increased risk of dementia. To our knowledge, this is the first study to investigate the …

Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …