Macrophages as tools and targets in cancer therapy
A Mantovani, P Allavena, F Marchesi… - Nature Reviews Drug …, 2022 - nature.com
Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
Hallmarks of cancer: new dimensions
D Hanahan - Cancer discovery, 2022 - AACR
The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity
of cancer phenotypes and genotypes into a provisional set of underlying principles. As …
of cancer phenotypes and genotypes into a provisional set of underlying principles. As …
A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors
AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin… - Cell, 2022 - cell.com
Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the
human microbiome, yet little is known about their role in human cancers. Pan-cancer …
human microbiome, yet little is known about their role in human cancers. Pan-cancer …
Targeting the gut microbiota for cancer therapy
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …
Immunology and immunotherapy of cholangiocarcinoma
Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
Activity‐based NIR enzyme fluorescent probes for the diagnosis of tumors and image‐guided surgery
H Li, D Kim, Q Yao, H Ge, J Chung, J Fan… - Angewandte …, 2021 - Wiley Online Library
Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …
edge tools for the investigation of cell biology and disease diagnosis because of their …
[HTML][HTML] Commensal microbiota promote lung cancer development via γδ T cells
Lung cancer is closely associated with chronic inflammation, but the causes of inflammation
and the specific immune mediators have not been fully elucidated. The lung is a mucosal …
and the specific immune mediators have not been fully elucidated. The lung is a mucosal …
NF-κB, inflammation, immunity and cancer: coming of age
K Taniguchi, M Karin - Nature Reviews Immunology, 2018 - nature.com
Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …
molecular lynchpin that links persistent infections and chronic inflammation to increased …
The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells
NN Liu, CX Yi, LQ Wei, JA Zhou, T Jiang, CC Hu… - Cancer Cell, 2023 - cell.com
Although polymorphic microbiomes have emerged as hallmarks of cancer, far less is known
about the role of the intratumor mycobiome as living microorganisms in cancer progression …
about the role of the intratumor mycobiome as living microorganisms in cancer progression …
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
R Singh, S Chandrashekharappa, SR Bodduluri… - Nature …, 2019 - nature.com
The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …