Voltage-gated sodium channels as insecticide targets

KS Silver, Y Du, Y Nomura, EE Oliveira… - Advances in insect …, 2014 - Elsevier
Voltage-gated sodium channels are critical for the generation and propagation of action
potentials. They are the primary target of several classes of insecticides, including DDT …

Molecular biology of insect sodium channels and pyrethroid resistance

K Dong, Y Du, F Rinkevich, Y Nomura, P Xu… - Insect biochemistry and …, 2014 - Elsevier
Voltage-gated sodium channels are essential for the initiation and propagation of the action
potential in neurons and other excitable cells. Because of their critical roles in electrical …

Biomarkers of type II synthetic pyrethroid pesticides in freshwater fish

A Kaviraj, A Gupta - BioMed research international, 2014 - Wiley Online Library
Type II synthetic pyrethroids contain an alpha‐cyano group which renders them more
neurotoxic than their noncyano type I counterparts. A wide array of biomarkers have been …

[HTML][HTML] A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure of Dengue Mosquito Control by Insecticides

K Hirata, O Komagata, K Itokawa… - PLoS neglected …, 2014 - journals.plos.org
The voltage-sensitive sodium (Na+) channel (Vssc) is the target site of pyrethroid
insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one …

Differential resistance of insect sodium channels with kdr mutations to deltamethrin, permethrin and DDT

MJ Burton, IR Mellor, IR Duce, TGE Davies… - Insect biochemistry and …, 2011 - Elsevier
Knockdown resistance (kdr) in insects, caused by inherited nucleotide polymorphisms in the
voltage-gated sodium channel (VGSC) gene, is a major threat to the efficacy of pyrethroid …

[HTML][HTML] High-resolution genetic mapping combined with transcriptome profiling reveals that both target-site resistance and increased detoxification confer resistance …

B De Beer, M Vandenhole, C Njiru, P Spanoghe… - Biology, 2022 - mdpi.com
Simple Summary The two-spotted spider mite Tetranychus urticae is an important pest on
agricultural crops worldwide. The widespread application of pyrethroid acaricides—such as …

A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids

Z Hu, Y Du, Y Nomura, K Dong - Insect biochemistry and molecular biology, 2011 - Elsevier
Voltage-gated sodium channels are the primary target of pyrethroid insecticides. Numerous
point mutations in sodium channel genes have been identified in pyrethroid-resistant insect …

Pyrethroids and their effects on ion channels

EN Wakeling, AP Neal… - Pesticides—Advances in …, 2012 - books.google.com
Ion channels are integral membrane proteins that are critical for neuronal function. They
form pores in the plasma membrane that allow certain ions to travel with their concentration …

Transmembrane potential polarization, calcium influx, and receptor conformational state modulate the sensitivity of the imidacloprid-insensitive neuronal insect …

B Bodereau-Dubois, O List, D Calas-List… - … of Pharmacology and …, 2012 - ASPET
Neonicotinoid insecticides act selectively on insect nicotinic acetylcholine receptors
(nAChRs). Recent studies revealed that their efficiency was altered by the phosphorylation …

植物源杀虫剂的研究进展

韩俊艳, 张立竹, 纪明山 - 中国农学通报, 2011 - cqvip.com
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