[HTML][HTML] Towards organoid culture without Matrigel

MT Kozlowski, CJ Crook, HT Ku - Communications biology, 2021 - nature.com
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Designing decellularized extracellular matrix‐based bioinks for 3D bioprinting

A Abaci, M Guvendiren - Advanced healthcare materials, 2020 - Wiley Online Library
Abstract 3D bioprinting is an emerging technology to fabricate tissues and organs by
precisely positioning cells into 3D structures using printable cell‐laden formulations known …

[HTML][HTML] Research progress in decellularized extracellular matrix-derived hydrogels

W Zhang, A Du, S Liu, M Lv, S Chen - Regenerative therapy, 2021 - Elsevier
Decellularized extracellular matrix (dECM) is widely used in regenerative medicine as a
scaffold material due to its unique biological activity and good biocompatibility. Hydrogel is a …

[HTML][HTML] Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal

M Tao, T Ao, X Mao, X Yan, R Javed, W Hou, Y Wang… - Bioactive materials, 2021 - Elsevier
Sterilization is the process of killing all microorganisms, while disinfection is the process of
killing or removing all kinds of pathogenic microorganisms except bacterial spores …

[HTML][HTML] Strategies for improving the 3D printability of decellularized extracellular matrix bioink

H Zhang, Y Wang, Z Zheng, X Wei, L Chen, Y Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract 3D bioprinting is a revolutionary technology capable of replicating native tissue and
organ microenvironments by precisely placing cells into 3D structures using bioinks …

[HTML][HTML] Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids

J Willemse, G van Tienderen, E van Hengel, I Schurink… - Biomaterials, 2022 - Elsevier
Human cholangiocyte organoids are promising for regenerative medicine applications, such
as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor …

Genetics, pathobiology and therapeutic opportunities of polycystic liver disease

P Olaizola, PM Rodrigues… - Nature Reviews …, 2022 - nature.com
Polycystic liver diseases (PLDs) are inherited genetic disorders characterized by
progressive development of intrahepatic, fluid-filled biliary cysts (more than ten), which …

[HTML][HTML] Recent advances in liver engineering with decellularized scaffold

Q Dai, W Jiang, F Huang, F Song, J Zhang… - … in Bioengineering and …, 2022 - frontiersin.org
Liver transplantation is currently the only effective treatment for patients with end-stage liver
disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors …