Decellularized extracellular matrix (dECM) hydrogels provide tissue-specific
microenvironments which accommodate physiological cellular phenotypes in 3D in vitro cell …

The integration of a bile drainage structure into engineered liver tissues is an important
issue in the advancement of liver regenerative medicine. Primary biliary cells, which play a …

Liver transplantation is the only curative therapy for end stage liver disease, but is limited by
the organ shortage, and is associated with the adverse consequences of …

The intricate electrophysiological functions and anatomical structures of spinal cord tissue
render the establishment of in vitro models for spinal cord-related diseases highly …

Bile duct injury is a common complication of hepatobiliary surgeries in clinical practice with
poorly satisfactory treatment outcomes. Implanting a tissue-engineered tubular scaffold for …

Organoids have been used to investigate the three-dimensional (3D) organization and
function of their respective organs. These self-organizing 3D structures offer a distinct …

Liver transplantation represents the only definitive treatment for patients with end-stage liver
disease. However, the shortage of liver donors provokes a dramatic gap between available …

Abstract 3D bioprinting has recently emerged as a successful biofabrication strategy for
replicating the complex in vivo hepatic milieu. Significant research advances in this field …

Liver is an essential organ that carries out multiple functions such as glycogen storage, the
synthesis of plasma proteins, and the detoxification of xenobiotics. Hepatocytes are the …

Cancer is one of the leading causes of death both in the United States and worldwide. The
dynamic microenvironment in which tumors grow consists of fibroblasts, immune cells …