In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

BACKGROUND The sperm chromatin of fertile men retains a small number of nucleosomes
that are enriched at developmental gene promoters and imprinted gene loci. This unique …

Abstract Endocrine-disrupting chemicals (EDCs), among which is the antiandrogen
vinclozolin (VCZ), have been reported to affect the male reproductive system. In this study …

Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

STUDY QUESTION What is the sperm DNA methylation status of imprinted genes in male
partners from couples experiencing recurrent pregnancy loss (RPL)? SUMMARY ANSWER …

BACKGROUND The subject of epigenetic risk of assisted reproduction treatment (ART),
initiated by reports on an increase of children with the Beckwith–Wiedemann imprinting …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Abstract The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held
to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted …