Aspalathin is a C-glucosyl dihydrochalcone that is abundantly present in Aspalathus
linearis. This endemic South African plant, belonging to the Cape Floristic region, is normally …

Increasing consumer bias toward natural products and the considerable wealth of
indigenous knowledge has precipitated an upturn in market-driven research into potentially …

We previously demonstrated that an aspalathin-enriched green rooibos extract (GRE)
reversed palmitate-induced insulin resistance in C2C12 skeletal muscle and 3T3-L1 fat cells …

Aspalathin (ASP) is a C-dihydrochalcone abundantly found in Aspalathus linearis. While we
have provide evidence that ASP can protect H9c2 cardiomyoblasts against doxorubicin …

Purpose Oxidative stress causes mitochondrial dysfunction in myocardial
ischaemia/reperfusion (I/R) as well as in obesity. Mitochondrial depolarization triggers …

Abstract Aspalathin (2′, 3, 4, 4′, 6′-pentahydroxy-3′-C-β-D-
glucopyranosyldihydrochalcone) is a natural C-linked glucosyl dihydrochalcone present in …

Natural compounds may bear promising therapeutic benefits against metabolic diseases
such as type 2 diabetes mellitus (T2DM), which are characterized by a state of insulin …

Objectives Rooibos tea, a very popular everyday beverage made of Aspalathus linearis
plant material and containing multiple polyphenolic compounds, reveals an expectation to …

Diabetic patients develop ischemic heart disease and strokes more readily. Following an
ischemic event, restoration of blood flow increases oxidative stress resulting in myocardial …

HIV-infection, certain antiretroviral drug classes, especially protease inhibitors (PI), and
obesity are associated with increased ischaemic heart disease (IHD) risk. However, the …