Qualitative sex differences in pain processing: emerging evidence of a biased literature
JS Mogil - Nature Reviews Neuroscience, 2020 - nature.com
Although most patients with chronic pain are women, the preclinical literature regarding pain
processing and the pathophysiology of chronic pain has historically been derived …
processing and the pathophysiology of chronic pain has historically been derived …
Emerging importance of satellite glia in nervous system function and dysfunction
Satellite glial cells (SGCs) closely envelop cell bodies of neurons in sensory, sympathetic
and parasympathetic ganglia. This unique organization is not found elsewhere in the …
and parasympathetic ganglia. This unique organization is not found elsewhere in the …
Acute inflammatory response via neutrophil activation protects against the development of chronic pain
M Parisien, LV Lima, C Dagostino… - Science translational …, 2022 - science.org
The transition from acute to chronic pain is critically important but not well understood. Here,
we investigated the pathophysiological mechanisms underlying the transition from acute to …
we investigated the pathophysiological mechanisms underlying the transition from acute to …
Pain-resolving immune mechanisms in neuropathic pain
Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
Astrocytes in chronic pain and itch
Astrocytes are critical for maintaining the homeostasis of the CNS. Increasing evidence
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
Pain and immunity: implications for host defence
Pain is a hallmark of tissue injury, inflammatory diseases, pathogen invasion and
neuropathy. It is mediated by nociceptor sensory neurons that innervate the skin, joints …
neuropathy. It is mediated by nociceptor sensory neurons that innervate the skin, joints …
Pain regulation by non-neuronal cells and inflammation
RR Ji, A Chamessian, YQ Zhang - Science, 2016 - science.org
Acute pain is protective and a cardinal feature of inflammation. Chronic pain after arthritis,
nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a …
nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a …
[HTML][HTML] Exercise-induced hypoalgesia in pain-free and chronic pain populations: state of the art and future directions
Exercise is considered an important component of effective chronic pain management and it
is well-established that long-term exercise training provides pain relief. In healthy, pain-free …
is well-established that long-term exercise training provides pain relief. In healthy, pain-free …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal …
Z Liu, X Yao, B Sun, W Jiang, C Liao, X Dai… - Free Radical Biology …, 2021 - Elsevier
Spinal cord injury (SCI) is a devastating injury that characterized by oxidative stress and
inflammatory response. Kaempferol is reported to be an anti-neuroinflammation in …
inflammatory response. Kaempferol is reported to be an anti-neuroinflammation in …