The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging
even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut …

Antimicrobial resistance (AMR) has become a major problem in public health leading to an
estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and …

The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the
development of new therapeutic agents against antibiotic resistance is in urgent demand …

The search for a natural antimicrobial agent is ongoing and critical because of the rise and
rapid proliferation of antibiotic-resistant pathogenic bacteria. The current study aims to …

Antibiotic resistance has become a pressing global health crisis, with bacterial infections
increasingly difficult to treat due to the emergence of multidrug resistance. This study aims to …

Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …

The cases of bacterial multidrug resistance are increasing every year and becoming a
serious concern for human health. Multidrug efflux pumps are key players in the formation of …

The global rise in antibiotic resistance, fueled by indiscriminate antibiotic usage in medicine,
aquaculture, agriculture, and the food industry, presents a significant public health …

The lipopolysaccharide, a microbial toxin, is one of the major causative agents of sepsis. P-
gp expression and its functions are altered during inflammation. LPS has been known to …