The forces that cells, tissues, and organisms exert on the surface of a soft substrate can be
measured using Traction Force Microscopy (TFM), an important and well-established …

Across diverse research and application areas, dynamic functionality—such as
programmable changes in biochemical property, in mechanical property, or in microscopic …

Mechanical forces drive critical cellular processes that are reflected in mechanical
phenotypes, or mechanotypes, of cells and their microenvironment. We present here …

Cancer cells exhibit metabolic plasticity to meet oncogene-driven dependencies while
coping with nutrient availability. A better understanding of how systemic metabolism impacts …

Mechanics, as a key physical factor which affects cell function and tissue regeneration, is
attracting the attention of researchers in the fields of biomaterials, biomechanics, and tissue …

Cardiomyocytes are the motor units that drive the contraction and relaxation of the heart.
Traditionally, testing of drugs for cardiotoxic effects has relied on primary cardiomyocytes …

Essential cellular processes such as cell adhesion, migration and division strongly depend
on mechanical forces. The standard method to measure cell forces is traction force …

The mechanical properties of cells and tissues help determine their architecture,
composition and function. Alterations to these properties are associated with many diseases …

Adherent biological cells generate traction forces on a substrate that play a central role for
migration, mechanosensing, differentiation, and collective behavior. The established method …

Cell-generated tractions play an important role in various physiological and pathological
processes such as stem-cell differentiation, cell migration, wound healing, and cancer …