Alzheimer's disease: epidemiology and clinical progression

AA Tahami Monfared, MJ Byrnes, LA White… - Neurology and …, 2022 - Springer
Alzheimer's disease (AD) is prevalent throughout the world and is the leading cause of
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …

[HTML][HTML] Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: pathogenic mechanisms and therapeutic potential

W Zhang, C Xu, J Sun, HM Shen, J Wang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is
characterized by memory loss and cognitive dysfunction. The accumulation of misfolded …

Global prevalence of mild cognitive impairment among older adults living in nursing homes: a meta-analysis and systematic review of epidemiological surveys

P Chen, H Cai, W Bai, Z Su, YL Tang… - Translational …, 2023 - nature.com
Mild cognitive impairment (MCI) is the early stage of cognitive impairment between the
expected cognitive decline of normal aging and the more serious decline of dementia. This …

Mild cognitive impairment among rural‐dwelling older adults in China: a community‐based study

L Cong, Y Ren, Y Wang, T Hou, Y Dong… - Alzheimer's & …, 2023 - Wiley Online Library
Background Epidemiological studies of mild cognitive impairment (MCI) and subtypes of
MCI have rarely focused on rural residents in China. Methods This population‐based study …

Prevalence of mild cognitive impairment in patients with hypertension: a systematic review and meta-analysis

J Qin, Z He, L Wu, W Wang, Q Lin, Y Lin… - Hypertension …, 2021 - nature.com
Mild cognitive impairment (MCI) is common in patients with hypertension. Prevalence
estimates of MCI in hypertensive patients are needed to guide both public health and clinical …

The hippocampal vulnerability to herpes simplex virus type I infection: relevance to Alzheimer's disease and memory impairment

SJ Yong, MH Yong, SL Teoh, T Soga… - Frontiers in cellular …, 2021 - frontiersin.org
Herpes simplex virus type 1 (HSV-1) as a possible infectious etiology in Alzheimer's disease
(AD) has been proposed since the 1980s. The accumulating research thus far continues to …

Instrumental activities of daily living trajectories and risk of mild cognitive impairment among Chinese older adults: results of the Chinese longitudinal healthy longevity …

J Yang, Y Zhang, S Shen, H Yu, L Yang… - Frontiers in Public …, 2023 - frontiersin.org
Background The association between the instrumental activities of daily living (IADL) score
and the risk of initial cognitive function impairment is inconclusive. We aimed to identify …

Cognitive frailty among community-dwelling rural elderly population of West Bengal in India

S Das - Asian Journal of Psychiatry, 2022 - Elsevier
Objectives There has been growing interest in the links between physical frailty and
cognitive impairment: both can increase the risk of emerging life-threatening health …

Peptidomimetics based on ammonium decasubstituted pillar [5] arenes: Influence of the alpha-amino acid residue nature on cholinesterase inhibition

A Nazarova, P Padnya, A Kharlamova, K Petrov… - Bioorganic …, 2023 - Elsevier
Cholinesterase inhibitors are a group of medicines that are widely used for the treatment of
cognitive impairments accompanying Alzheimer's disease as well as for the treatment of …

Associations of bilateral vestibulopathy with cognition in older adults matched with healthy controls for hearing status

J Bosmans, H Gommeren, G Mertens… - … –Head & Neck …, 2022 - jamanetwork.com
Importance Recent literature suggests there may be a significant effect of the vestibular
system on cognition and visuospatial processing. Given the increasing prevalence of …