Cell death pathways of particulate matter toxicity

MS Peixoto, MF de Oliveira Galvão, SRB de Medeiros - Chemosphere, 2017 - Elsevier
Humans are exposed to various complex mixtures of particulate matter (PM) from different
sources. Long-term exposure to high levels of these particulates has been linked to a …

Mitochondria and mitochondrial DNA as relevant targets for environmental contaminants

DA Roubicek, NC de Souza-Pinto - Toxicology, 2017 - Elsevier
The mitochondrial DNA (mtDNA) is a closed circular molecule that encodes, in humans, 13
polypeptides components of the oxidative phosphorylation complexes. Integrity of the …

Organic extracts of urban air pollution particulate matter (PM2. 5)-induced genotoxicity and oxidative stress in human lung bronchial epithelial cells (BEAS-2B cells)

SM Oh, HR Kim, YJ Park, SY Lee, KH Chung - Mutation Research/Genetic …, 2011 - Elsevier
Traffic is a major source of particulate matter (PM), and ultrafine particulates and traffic
intensity probably contribute significantly to PM-related health effects. As a strong …

[HTML][HTML] Biomass burning in the Amazon region causes DNA damage and cell death in human lung cells

N de Oliveira Alves, AT Vessoni, A Quinet… - Scientific reports, 2017 - nature.com
Most of the studies on air pollution focus on emissions from fossil fuel burning in urban
centers. However, approximately half of the world's population is exposed to air pollution …

Airborne urban particles (Milan winter-PM2. 5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization

M Gualtieri, J Øvrevik, S Mollerup, N Asare… - Mutation Research …, 2011 - Elsevier
Airborne particulate matter (PM) is considered to be an important contributor to lung
diseases. In the present study we report that Milan winter-PM2. 5 inhibited proliferation in …

Biomass burning particles in the Brazilian Amazon region: Mutagenic effects of nitro and oxy-PAHs and assessment of health risks

MF de Oliveira Galvao, N de Oliveira Alves… - Environmental …, 2018 - Elsevier
Emissions from burning of biomass in the Amazon region have adverse effects on the
environment and human health. Herein, particulate matter (PM) emitted from biomass …

Air pollution and genomic instability: The role of particulate matter in lung carcinogenesis

M Santibáñez-Andrade, EM Quezada-Maldonado… - Environmental …, 2017 - Elsevier
In this review, we summarize and discuss the evidence regarding the interaction between air
pollution, especially particulate matter (PM), and genomic instability. PM has been widely …

Correlation of α/γ-Fe2O3 nanoparticles with the toxicity of particulate matter originating from subway tunnels in Seoul stations, Korea

Y Lee, HS Chun, JY Moon, JS Choi, D Park… - Journal of Hazardous …, 2020 - Elsevier
According to the increasing concern about particulate matter (PM) pollution at subway
systems, particularly its potentially severe effects on human health, this study investigated …

LncRNA LOC101927514 regulates PM2. 5-driven inflammation in human bronchial epithelial cells through binding p-STAT3 protein

Y Tan, YY Wang, YF Zou, CL Zhou, YN Yi, YH Ling… - Toxicology letters, 2020 - Elsevier
Long-term exposure to fine particulate matter (PM 2.5) may cause or exacerbate many
diseases, including respiratory inflammation. However, the full mechanism is not yet fully …

“Risk is in the air”: polycyclic aromatic hydrocarbons, metals and mutagenicity of atmospheric particulate matter in a town of Northern Italy (Respira study)

D Feretti, R Pedrazzani, E Ceretti, M Dal Grande… - … /Genetic Toxicology and …, 2019 - Elsevier
Air pollution has well-known harmful effects on human beings, causing both acute and
chronic diseases. Some data suggest that genetic damage occurring early in life may …