Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) or without (CRSsNP) are
chronic respiratory diseases. These two disorders often co-exist based on common …

Biologics, including omalizumab, mepolizumab, benralizumab, and dupilumab, targeting
downstream IgE, cytokines IL-5, and IL-4/13, respectively, have shown promising effects in …

The assessment and management of patients with asthma is challenging because of the
complexity of the underlying inflammatory mechanisms and heterogeneity of their clinical …

Das Management von Asthma hat sich in den letzten Jahrzehnten fundamental gewandelt.
Die vorliegende Leitlinie zur Diagnostik und Therapie von Asthma wurde für pneumologisch …

Exhaled nitric oxide (NO) production, upregulated by inflammatory cytokines and mediators
in central and peripheral airways, can be easily and non-invasively detected in exhaled air …

The detection of nitric oxide in human exhaled breath (EB) has received wide attention due
to its close relationship with respiratory tract inflammation. Herein, a ppb-level NO x …

Cancers, chronic diseases and respiratory infections are major causes of mortality and
present diagnostic and therapeutic challenges for health care. There is an unmet medical …

Uncontrolled asthma in the elderly is a public health issue recognized in developed
countries such as the United States and among the European Union, both from patient …

Objective Asthma control is generally monitored by assessing symptoms and lung function.
However, optimal treatment is also dependent on the type and extent of airway inflammation …