Background Mean nocturnal baseline impedance (MNBI) and postreflux swallow‐induced
peristaltic wave (PSPW) index are novel impedance‐based markers of reflux, but the effect …

Introduction: Medical therapy of gastroesophageal reflux disease (GERD) is based on the
use of proton pump inhibitors (PPIs) as first choice treatment. Despite their effectiveness …

Objective GERD is among the most common outpatient disease processes encountered by
clinicians on a daily basis. This review provides insights about how to approach GERD in …

Background Symptomatic breakthrough in proton pump inhibitor (PPI)‐treated gastro‐
oesophageal reflux disease (GERD) patients is a common problem with a range of …

Background The comparative efficacy and safety of medical therapies for gastro‐
esophageal reflux symptoms in endoscopy‐negative reflux disease is unclear. We …

The potential role of potassium-competitive acid blockers in... : Current Opinion in
Gastroenterology The potential role of potassium-competitive acid blockers in the treatment of …

The most recent iteration of the classifications for functional esophageal disorders, Rome IV,
proposed relevant modifications of the previous definitions for Rome III. They specifically …

The focus on a symptom-based definition for gastroesophageal reflux disease (GERD) in
adults and children has contributed to widespread use of acid suppression medications in …

Background Microscopic inflammation and impairment of the esophageal epithelial barrier
are considered relevant for perception of symptoms in patients with nonerosive reflux …

Nonerosive reflux disease (NERD) is a common condition and the most frequent phenotype
of gastroesophageal reflux disease (GERD). NERD is extremely heterogeneous and …