Monocyte subsets involved in the development of systemic lupus erythematosus and rheumatoid arthritis
S Hirose, Q Lin, M Ohtsuji, H Nishimura… - International …, 2019 - academic.oup.com
AbstractMonocytes are evolutionally conserved innate immune cells that play essential roles
for the protection of the host against pathogens and also produce several inflammatory …
for the protection of the host against pathogens and also produce several inflammatory …
The complex association of FcγRIIb with autoimmune susceptibility
JS Verbeek, S Hirose, H Nishimura - Frontiers in Immunology, 2019 - frontiersin.org
FcγRIIb is the only inhibitory Fc receptor and controls many aspects of immune and
inflammatory responses. The observation 19 years ago that Fc γ RIIb−/− mice generated by …
inflammatory responses. The observation 19 years ago that Fc γ RIIb−/− mice generated by …
FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation
AN Barlev, S Malkiel, I Kurata-Sato… - The Journal of …, 2022 - Am Soc Clin Investig
FcγRIIB is an inhibitory receptor expressed throughout B cell development. Diminished
expression or function is associated with lupus in mice and humans, in particular through an …
expression or function is associated with lupus in mice and humans, in particular through an …
Adenovirus-mediated overexpression of FcγRIIB attenuates pulmonary inflammation and fibrosis
Z Zhang, Z Cao, L Hou, M Song, Y Zhou… - American Journal of …, 2023 - atsjournals.org
Progressive fibrosing interstitial lung diseases (PF-ILDs) result in high mortality and lack
effective therapies. The pathogenesis of PF-ILDs involves macrophages driving …
effective therapies. The pathogenesis of PF-ILDs involves macrophages driving …
The effect of soluble epoxide hydrolase inhibition on the mononuclear phagocyte system during inflammation
OV Bracken - 2023 - discovery.ucl.ac.uk
Evidence suggests a role for Cytochrome P450 metabolites, namely the epoxy-oxylipins, in
facilitating the inflammatory response. The soluble epoxide hydrolase (sEH) enzyme …
facilitating the inflammatory response. The soluble epoxide hydrolase (sEH) enzyme …