Pneumonia research to reduce childhood mortality in the developing world
JAG Scott, WA Brooks, JSM Peiris… - The Journal of …, 2008 - Am Soc Clin Investig
Pneumonia is an illness, usually caused by infection, in which the lungs become inflamed
and congested, reducing oxygen exchange and leading to cough and breathlessness. It …
and congested, reducing oxygen exchange and leading to cough and breathlessness. It …
Human respiratory syncytial virus: pathogenesis, immune responses, and current vaccine approaches
SA Taleb, AA Al Thani, K Al Ansari… - European Journal of …, 2018 - Springer
Respiratory syncytial virus continues to pose a serious threat to the pediatric populations
worldwide. With a genomic makeup of 15,200 nucleotides, the virus encodes for 11 proteins …
worldwide. With a genomic makeup of 15,200 nucleotides, the virus encodes for 11 proteins …
[HTML][HTML] The burden of respiratory syncytial virus infection in young children
CB Hall, GA Weinberg, MK Iwane… - … England Journal of …, 2009 - Mass Medical Soc
Background The primary role of respiratory syncytial virus (RSV) in causing infant
hospitalizations is well recognized, but the total burden of RSV infection among young …
hospitalizations is well recognized, but the total burden of RSV infection among young …
Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance
Background. Although necessary for developing a rationale for vaccination, the burden of
severe respiratory syncytial virus (RSV) disease in children in resource-poor settings …
severe respiratory syncytial virus (RSV) disease in children in resource-poor settings …
Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology
MR Murawski, LW McGinnes, RW Finberg… - Journal of …, 2010 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of serious respiratory infections in
children as well as a serious cause of disease in elderly and immunosuppressed …
children as well as a serious cause of disease in elderly and immunosuppressed …
Respiratory syncytial virus matrix protein is sufficient and necessary to remodel host mitochondria in infection
MJ Hu, MA Bogoyevitch, DA Jans - Cells, 2023 - mdpi.com
Although respiratory syncytial virus (RSV) is the most common cause of respiratory infection
in infants, immunosuppressed adults and the elderly worldwide, there is no licensed RSV …
in infants, immunosuppressed adults and the elderly worldwide, there is no licensed RSV …
Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins
LW McGinnes, KA Gravel, RW Finberg… - Journal of …, 2011 - Am Soc Microbiol
Human respiratory syncytial virus (RSV) is a serious respiratory pathogen in infants and
young children as well as elderly and immunocompromised populations. However, no RSV …
young children as well as elderly and immunocompromised populations. However, no RSV …
Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice
T Kamphuis, T Meijerhof, T Stegmann, J Lederhofer… - PloS one, 2012 - journals.plos.org
Respiratory Syncytial Virus (RSV) is a major cause of viral brochiolitis in infants and young
children and is also a significant problem in elderly and immuno-compromised adults. To …
children and is also a significant problem in elderly and immuno-compromised adults. To …
Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African Children
TL Kresfelder, R Janssen, L Bont… - Journal of medical …, 2011 - Wiley Online Library
Respiratory syncytial virus is a leading cause of lower respiratory tract infection in infants.
Disease severity has been linked to host immune responses and polymorphisms in genes …
Disease severity has been linked to host immune responses and polymorphisms in genes …
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV …
TR Johnson, S Rao, RA Seder, M Chen, BS Graham - Vaccine, 2009 - Elsevier
Agonists for TLR7, TLR8, and TLR9 have been shown to enhance vaccine immunogenicity.
We evaluated the impact of TLR activation on RSV disease in a murine model by …
We evaluated the impact of TLR activation on RSV disease in a murine model by …