[HTML][HTML] Oxidative stress and microRNAs in endothelial cells under metabolic disorders

M Minjares, W Wu, JM Wang - Cells, 2023 - mdpi.com
Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

[HTML][HTML] Essential hypertension and oxidative stress: novel future perspectives

C Franco, E Sciatti, G Favero, F Bonomini… - International Journal of …, 2022 - mdpi.com
Among cardiovascular diseases, hypertension is one of the main risk factors predisposing to
fatal complications. Oxidative stress and chronic inflammation have been identified as …

[HTML][HTML] Cardiovascular protection with a long-acting GLP-1 receptor agonist liraglutide: an experimental update

C Vandemark, J Nguyen, ZQ Zhao - Molecules, 2023 - mdpi.com
Angiotensin II (Ang II), a peptide hormone generated as part of the renin–angiotensin
system, has been implicated in the pathophysiology of many cardiovascular diseases such …

1, 8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway

M Chen, Q Hu, S Wang, L Tao, X Hu, X Shen - European Journal of …, 2023 - Elsevier
Our previous data confirmed that 1, 8-Cineole had an antihypertensive effect in animal
models. However, it is unclear whether antihypertension is dependent on the protective …

[HTML][HTML] Exosomes of endothelial progenitor cells repair injured vascular endothelial cells through the Bcl2/Bax/Caspase-3 pathway

W Tan, Y Li, L Ma, X Fu, Q Long, F Yan, W Li, X Liu… - Scientific Reports, 2024 - nature.com
The main objective of this study is to evaluate the influence of exosomes derived from
endothelial progenitor cells (EPC-Exo) on neointimal formation induced by balloon injury in …

Pharmacological modulation of vascular ageing: A review from VascAgeNet

L Roth, S Dogan, BG Tuna, T Aranyi, S Benitez… - Ageing research …, 2023 - Elsevier
Vascular ageing, characterized by structural and functional changes in blood vessels of
which arterial stiffness and endothelial dysfunction are key components, is associated with …

Endocan as a marker of endothelial dysfunction in hypertension: a systematic review and meta-analysis

AH Behnoush, A Khalaji, P Bahiraie… - Hypertension …, 2023 - nature.com
Hypertension is one of the foremost risk factors for cardiovascular disease and a significant
cause of death worldwide. Importantly, endothelial dysfunction (ED) is one of the primary …

[HTML][HTML] Association of remnant cholesterol with hypertension, type 2 diabetes, and their coexistence: the mediating role of inflammation-related indicators

Y Wu, Q Wei, H Li, H Yang, Y Wu, Y Yu, Q Chen… - Lipids in Health and …, 2023 - Springer
Purpose Cholesterol metabolism is a risk factor for cardiovascular disease, and recent
studies have shown that cholesterol metabolism poses a residual risk of cardiovascular …

Vascular Inflammation and Smooth Muscle Contractility: The Role of Nox1-Derived Superoxide and LRRC8 Anion Channels

FS Lamb, H Choi, MR Miller, RJ Stark - Hypertension, 2024 - Am Heart Assoc
Vascular inflammation underlies the development of hypertension, and the mechanisms by
which it increases blood pressure remain the topic of intense investigation. Proinflammatory …

[HTML][HTML] The vanilloid (capsaicin) receptor TRPV1 in blood pressure regulation: a novel therapeutic target in hypertension?

A Szallasi - International journal of molecular sciences, 2023 - mdpi.com
Today's sedentary lifestyle with excess food and little exercise increases the number of
people with hypertension, a major risk factor for stroke. New knowledge of treatments in this …