[HTML][HTML] Air pollution and COVID-19: the role of particulate matter in the spread and increase of COVID-19's morbidity and mortality

S Comunian, D Dongo, C Milani… - International journal of …, 2020 - mdpi.com
Sars-Cov-2 virus (COVID-19) is a member of the coronavirus family and is responsible for
the pandemic recently declared by the World Health Organization. A positive correlation has …

The effects of heavy metals on human metabolism

Z Fu, S Xi - Toxicology mechanisms and methods, 2020 - Taylor & Francis
As technology continues to advance, heavy metals in drinking water have exceeded
recommended limits from regulators around the world. The main source of human exposure …

[HTML][HTML] Ferroptosis mechanisms involved in neurodegenerative diseases

CO Reichert, FA de Freitas, J Sampaio-Silva… - International journal of …, 2020 - mdpi.com
Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

[HTML][HTML] Oxidative stress: a key modulator in neurodegenerative diseases

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2019 - mdpi.com
Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

The toxicology of mercury: Current research and emerging trends

G Bjørklund, M Dadar, J Mutter, J Aaseth - Environmental research, 2017 - Elsevier
Mercury (Hg) is a persistent bio-accumulative toxic metal with unique physicochemical
properties of public health concern since their natural and anthropogenic diffusions still …

[HTML][HTML] The role of interleukin-6 signaling in nervous tissue

M Rothaug, C Becker-Pauly, S Rose-John - Biochimica et Biophysica Acta …, 2016 - Elsevier
Abstract The cytokine interleukin-6 (IL-6) plays a critical role in the pathogenesis of
inflammatory disorders and in the physiological homeostasis of neural tissue. Profound …

[HTML][HTML] Current knowledge on endocrine disrupting chemicals (EDCs) from animal biology to humans, from pregnancy to adulthood: highlights from a national Italian …

ME Street, S Angelini, S Bernasconi, E Burgio… - International journal of …, 2018 - mdpi.com
Wildlife has often presented and suggested the effects of endocrine disrupting chemicals
(EDCs). Animal studies have given us an important opportunity to understand the …

[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives

KD Fasae, AO Abolaji, TR Faloye, AY Odunsi… - Journal of Trace …, 2021 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …

Neurodegenerative and neurological disorders by small inhaled particles

HJ Heusinkveld, T Wahle, A Campbell, RHS Westerink… - Neurotoxicology, 2016 - Elsevier
The world⿿ s population is steadily ageing and as a result, health conditions related to
ageing, such as dementia, have become a major public health concern. In 2001, it was …