Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Kidney stone disease causes significant morbidity and increases health care utilization. In
this work, we decipher the cellular and molecular niche of the human renal papilla in …

Global quantification of protein abundances in single cells could provide direct information
on cellular phenotypes and complement transcriptomics measurements. However, single …

The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks …

Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

The mechanistic target of rapamycin (mTOR) signaling pathway plays a major role in key
cellular processes including metabolism and differentiation; however, the role of mTOR in …

Environmental cues influence the highly dynamic morphology of microglia. Strategies to
characterize these changes usually involve user-selected morphometric features, which …

Drug‐resistant bacterial infection impairs tissue regeneration and is a challenging clinical
problem. Metal–organic frameworks (MOFs)‐based photodynamic therapy (PDT) opens up …

Abstract Tumor-associated macrophages (TAMs), one of the most abundant immune
components in gastric cancer (GC), are difficult to characterize due to their heterogeneity …