Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …

Diseases of the lung account for more than 5 million deaths worldwide and are a healthcare
burden. Improving clinical outcomes, including mortality and quality of life, involves a holistic …

The lack of physiologically relevant in vitro models has hampered progress in understanding
human lung development and disease. Here, we describe a protocol in which human …

COVID-19 emerged in September 2020 as a disease caused by the virus SARS-CoV-2. The
disease presented as pneumonia at first but later was shown to cause multisystem infections …

Organoids have emerged as a powerful tool for understanding the biology of the respiratory,
digestive, nervous as well as urinary system, investigating infections, and developing new …

Transwell-based airway models have become increasingly important to study the effects of
respiratory diseases and drug treatment at the air-liquid interface of the lung epithelial …

Organoids are intricate 3D conglomerations of self-organized cells that bear cellular and
structural resemblance to organs. Also coined" mini-organs," organoids are able to …