RNA splicing factors in normal hematopoiesis and hematologic malignancies: novel therapeutic targets and strategies

Z Li, Z He, J Wang, G Kong - Journal of Leukocyte Biology, 2023 - academic.oup.com
RNA splicing, a crucial transesterification-based process by which noncoding regions are
removed from premature RNA to create mature mRNA, regulates various cellular functions …

Exploration of mRNAs and miRNA classifiers for various ATLL cancer subtypes using machine learning

MZ Ghobadi, R Emamzadeh, E Afsaneh - BMC cancer, 2022 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a cancer disease that is
developed due to the infection by human T-cell leukemia virus type 1. It can be classified …

[PDF][PDF] The speech-language processing model for managing the neuro-muscle disorder patients by using deep learning

NYC Sivakumar, A Shankar - NeuroQuantology, 2022 - researchgate.net
In general, prolonged contraction of skeletal muscle fibers is the clinical hallmark of
neurodegenerative disease. The primary symptoms are caused by tetanospasm, a …

Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus

MZ Ghobadi, E Afsaneh, R Emamzadeh… - BMC Medical …, 2023 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type
of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell …

Identification of New Key genes and their association with breast Cancer occurrence and poor survival using in Silico and in Vitro methods

R Ali, A Sultan, R Ishrat, S Haque, NJ Khan, MA Prieto - Biomedicines, 2023 - mdpi.com
Breast cancer is one of the most prevalent types of cancer diagnosed globally and continues
to have a significant impact on the global number of cancer deaths. Despite all efforts of …

Gene biomarkers and classifiers for various subtypes of HTLV-1-caused ATLL cancer identified by a combination of differential gene co‑expression and support vector …

M Zarei Ghobadi, E Afsaneh, R Emamzadeh - Medical Microbiology and …, 2023 - Springer
Adult T-cell leukemia/lymphoma (ATLL) is pathogen-caused cancer that is progressed after
the infection by human T-cell leukemia virus type 1. Four significant subtypes comprising …

Highlighting the role of immune responses, cell death and the nervous system in acute rotavirus infection using weighted gene co-expression network analysis

S Samadizadeh, A Vaez, Z Jamalpoor… - Future Virology, 2023 - Taylor & Francis
Aim: Identifying genes and pathways involved in various stages of rotavirus infection could
facilitate the mapping of the interactions between the virus and host. Materials & methods …

Privacy-Preserving Identification of Cancer Subtype-Specific Driver Genes Based on Multigenomics Data with Privatedriver

J Song, Z Song, J Zhang, Y Gong - Journal of Computational …, 2024 - liebertpub.com
Identifying cancer subtype-specific driver genes from a large number of irrelevant
passengers is crucial for targeted therapy in cancer treatment. Recently, the rapid …

Quantum machine learning for untangling the real-world problem of cancers classification based on gene expressions

MZ Ghoabdi, E Afsaneh - bioRxiv, 2023 - biorxiv.org
Quantum machine learning algorithms using the power of quantum computing provide fast-
developing approaches for solving complicated problems and speeding-up calculations for …

Disulfidptosis‐related PABPC3 promotes tumor progression and inhibits immune activity in osteosarcoma

Y Cao, S Wu, Y Gu, YH Wong, Y Shi… - The Journal of Gene …, 2024 - Wiley Online Library
Background Osteosarcoma is a very aggressive bone tumor mainly affecting teens and
young adults. Disulfidptosis is a metabolic‐related form of regulated cell death. However, the …