Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

The shortage of donor livers considered suitable for transplantation has driven the
development of novel methods for organ preservation and reconditioning. Machine …

Ex situ dual hypothermic oxygenated machine perfusion (DHOPE) and normothermic
machine perfusion (NMP) of donor livers may have a complementary effect when applied …

This article summarizes strategies to protect the liver from injuries caused by ischemia and
reperfusion. Three different sections (ie, surgical and pharmacologic strategies and gene …

Objective: Transplantation of organs retrieved after cardiac arrest could increase the donor
organ supply. However, the combination of warm ischemia and cold preservation is highly …

Treatment of injured donor lungs ex vivo to accelerate organ recovery and ameliorate
reperfusion injury could have a major impact in lung transplantation. We have recently …

With increasing demand for donor organs for transplantation, machine perfusion (MP)
promises to be a beneficial alternative preservation method for donor livers, particularly …

Donors after cardiac death (DCD) suffer irreversible cardiac arrest prior to donation. We
describe our liver transplant experience with DCD whose cardiac arrest is unexpected, not …

Solid organ transplantation is one of the most remarkable and dramatic therapeutic
advances in medicine during the past 60 years. This field has progressed initially from what …

The present review discusses strategies for minimizing the ischemia/reperfusion injury (IRI)
experienced during liver surgery and transplantation. We present the experimental models …