Colorectal cancer (CRC) is the fourth commonest type of malignancy after breast, lung and
prostate in the USA and accounts for approximately 49,190 deaths annually in USA alone …

Background: Previous studies suggest that sex steroids influence colorectal cancer (CRC)
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …

Drinking coffee has been associated with the development of several endocrine-related
cancers. The interpretation of these data has often been limited to the role that caffeine …

Polymers have been utilized to deliver the drug to targeted site in controlled manner,
achieving the high-therapeutic efficacy. Polymeric drug conjugates having variable ligands …

Background KRAS mutations are frequently found in colorectal cancer (CRC) indicating the
importance of its genotyping in the study of the molecular mechanisms behind this disease …

Although somatic alterations in CAG repeats in the androgen receptor (AR) gene have been
suggested to predispose to colorectal cancer, less is known about AR in colorectal cancer …

This study aimed to evaluate the modulatory role of sex-related hormone estradiol on cancer
stem cells with the origin of colorectal adenocarcinoma in vitro. Cancer stem cells were …

Abstract Pregnancy‐associated cancer (PAC), defined as cancers diagnosed during
pregnancy or the first year after delivery, affects one to two in every 1000 pregnancies …

Microsatellite instability (MSI) in tumors results in an accumulation of mutations in (target)
genes. Previous studies suggest that the profile of target genes differs according to tumor …

Background Among the sex hormones, oestrogen may play a role in colorectal cancer,
particularly in conjunction with oestrogen receptor-β (ERβ). The expression of ERβ isoform …