[HTML][HTML] Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics

LE McCoubrey, A Favaron, A Awad, M Orlu… - Journal of Controlled …, 2023 - Elsevier
Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …

Advancing pharmacy and healthcare with virtual digital technologies

SJ Trenfield, A Awad, LE McCoubrey… - Advanced Drug Delivery …, 2022 - Elsevier
Digitalisation of the healthcare sector promises to revolutionise patient healthcare globally.
From the different technologies, virtual tools including artificial intelligence, blockchain …

Electrospun Janus core (ethyl cellulose//polyethylene oxide)@ shell (hydroxypropyl methyl cellulose acetate succinate) hybrids for an enhanced colon-targeted …

J Zhou, T Yi, Z Zhang, DG Yu, P Liu, L Wang… - … Composites and Hybrid …, 2023 - Springer
Structural polymeric nanohybrids is presently a popular topic and can be conceived for
numerous functional applications, including the pH-sensitive oral colon-targeted drug …

Polysaccharide 3D printing for drug delivery applications

A Zamboulis, G Michailidou, I Koumentakou… - Pharmaceutics, 2022 - mdpi.com
3D printing, or additive manufacturing, has gained considerable interest due to its versatility
regarding design as well as in the large choice of materials. It is a powerful tool in the field of …

[HTML][HTML] 3D printed infliximab suppositories for rectal biologic delivery

A Awad, A Goyanes, M Orlu, S Gaisford… - International Journal of …, 2023 - Elsevier
Infliximab is a monoclonal antibody that plays an important role in the management and
treatment of chronic inflammatory bowel diseases (IBD). Due to its macromolecular structure …

Phthalate toxicity mechanisms: An update

CG Sree, V Buddolla, BA Lakshmi, YJ Kim - Comparative Biochemistry and …, 2023 - Elsevier
Phthalates are one of the most widely used plasticizers in polymer products, and they are
increasingly being exposed to people all over the world, generating health concerns …

Prediction of solid-state form of SLS 3D printed medicines using NIR and Raman spectroscopy

SJ Trenfield, P Januskaite, A Goyanes, D Wilsdon… - Pharmaceutics, 2022 - mdpi.com
Selective laser sintering (SLS) 3D printing is capable of revolutionising pharmaceutical
manufacturing, by producing amorphous solid dispersions in a one-step manufacturing …

Inkjet printing of pharmaceuticals

P Carou‐Senra, L Rodríguez‐Pombo… - Advanced …, 2024 - Wiley Online Library
Inkjet printing (IJP) is an additive manufacturing process that selectively deposits ink
materials, layer‐by‐layer, to create 3D objects or 2D patterns with precise control over their …

[HTML][HTML] Advancing oral delivery of biologics: Machine learning predicts peptide stability in the gastrointestinal tract

F Wang, N Sangfuang, LE McCoubrey, V Yadav… - International Journal of …, 2023 - Elsevier
The oral delivery of peptide therapeutics could facilitate precision treatment of numerous
gastrointestinal (GI) and systemic diseases with simple administration for patients. However …

[HTML][HTML] The role and mechanism of flavonoid herbal natural products in ulcerative colitis

JC Xue, S Yuan, H Meng, XT Hou, J Li… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine that presents
clinically with abdominal pain, mucopurulent stools, and posterior urgency. The lesions of …