Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs)
are tremendous, the design and discovery of new candidates remain a time and cost …

Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Mitochondrial dysfunction is a critical factor contributing to oxidative stress and apoptosis in
ischemia‐reperfusion (I/R) diseases. Mitoquinone (MitoQ) is a mitochondria‐targeted …

Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings.
Mitochondria are sensitive organelles that are readily damaged following ischemia and …

Normothermic machine perfusion (NMP) has emerged as a promising tool for the
preservation, viability assessment, and repair of deceased-donor kidneys prior to …

Transplanted organs are subjected to harmful conditions through stopping blood flow,
hypothermic storage of the graft, and subsequent reperfusion. In particular, kidneys donated …

Significance: Nutraceuticals are ingested for health benefits, in addition to their general
nutritional value. These dietary supplements have become increasingly popular since the …

The increasing number of patients on the kidney transplant waiting list underlines the need
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …

Background: Renal diseases remain an increasing public health issue affecting millions of
people. The kidney is a highly energetic organ that is rich in mitochondria. Numerous …