[HTML][HTML] Age-related changes in Folliculogenesis and potential modifiers to improve fertility outcomes-A narrative review

E Esencan, G Beroukhim, DB Seifer - Reproductive biology and …, 2022 - Springer
Reproductive aging is characterized by a decline in oocyte quantity and quality, which is
directly associated with a decline in reproductive potential, as well as poorer reproductive …

[HTML][HTML] Ovarian aging: molecular mechanisms and medical management

J Tesarik, M Galán-Lázaro… - International journal of …, 2021 - mdpi.com
This is a short review of the basic molecular mechanisms of ovarian aging, written with a
particular focus on the use of this data to improve the diagnostic and therapeutic protocols …

[HTML][HTML] Growth hormone in fertility and infertility: Mechanisms of action and clinical applications

CW Chang, YW Sung, YW Hsueh, YY Chen… - Frontiers in …, 2022 - frontiersin.org
Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

[HTML][HTML] Growth hormone cotreatment for poor responders undergoing in vitro fertilization cycles: a systematic review and meta-analysis

M Cozzolino, GN Cecchino, G Troiano, C Romanelli - Fertility and sterility, 2020 - Elsevier
Objective To evaluate the effectiveness of growth hormone (GH) supplementation in
improving the in vitro fertilization (IVF) outcomes of poor responders. Design Systematic …

[HTML][HTML] Impact of NAD+ metabolism on ovarian aging

J Liang, F Huang, Z Song, R Tang, P Zhang, R Chen - Immunity & Ageing, 2023 - Springer
Abstract Nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular redox
reactions, is closely associated with age-related functional degeneration and metabolic …

[HTML][HTML] Facilitation of ovarian response by mechanical force—Latest insight on fertility improvement in women with poor ovarian response or primary ovarian …

CL Chang - International journal of molecular sciences, 2023 - mdpi.com
The decline in fertility in aging women, especially those with poor ovarian response (POR)
or primary ovarian insufficiency (POI), is a major concern for modern IVF centers. Fertility …

[HTML][HTML] Melatonin: multi-target mechanism against diminished ovarian reserve based on network pharmacology

L Yang, H Xu, Y Chen, C Miao, Y Zhao… - Frontiers in …, 2021 - frontiersin.org
Background Diminished ovarian reserve (DOR) significantly increases the risk of female
infertility and contributes to reproductive technology failure. Recently, the role of melatonin in …

[HTML][HTML] Importance of IGF-I levels in IVF: potential relevance for growth hormone (GH) supplementation

N Gleicher, SK Darmon, E Molinari, P Patrizio… - Journal of assisted …, 2022 - Springer
Purpose Growth hormone (GH) supplementation in association with in vitro fertilization (IVF)
is worldwide again increasing, even though study outcomes have been discrepant. Since …

Fertility issues in hypopituitarism

J Chen, JJ Chang, EH Chung, RB Lathi… - Reviews in Endocrine …, 2024 - Springer
Women with hypopituitarism have lower fertility rates and worse pregnancy outcomes than
women with normal pituitary function. These disparities exist despite the use of assisted …

[HTML][HTML] The conundrum of poor ovarian response: from diagnosis to treatment

P Giannelou, M Simopoulou, S Grigoriadis, E Makrakis… - Diagnostics, 2020 - mdpi.com
Despite recent striking advances in assisted reproductive technology (ART), poor ovarian
response (POR) diagnosis and treatment is still considered challenging. Poor responders …