Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms
TS Jensen, NB Finnerup - The Lancet Neurology, 2014 - thelancet.com
Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …
Reward and motivation in pain and pain relief
E Navratilova, F Porreca - Nature neuroscience, 2014 - nature.com
Pain is fundamentally unpleasant, a feature that protects the organism by promoting
motivation and learning. Relief of aversive states, including pain, is rewarding. The …
motivation and learning. Relief of aversive states, including pain, is rewarding. The …
Editorial review (thematic issue: An update on central sensitivity syndromes and the issues of nosology and psychobiology)
MB Yunus - Current rheumatology reviews, 2015 - ingentaconnect.com
Central sensitization (CS), simply defined as an amplified response of the central nervous
system to peripheral input, is a concept of great importance in clinical medicine. It has …
system to peripheral input, is a concept of great importance in clinical medicine. It has …
Composition, structure and flavor mechanism of numbing substances in Chinese prickly ash in the genus Zanthoxylum: A review
J Luo, J Ke, X Hou, S Li, Q Luo, H Wu, G Shen, Z Zhang - Food Chemistry, 2022 - Elsevier
Chinese prickly ash is known for producing a typical pungent sensation in Sichuan Cuisine.
Accumulating evidence suggest a series of health benefits and pharmacological effects …
Accumulating evidence suggest a series of health benefits and pharmacological effects …
Spinal cord injury pain: mechanisms and management
NB Finnerup, C Baastrup - Current pain and headache reports, 2012 - Springer
Patients with spinal cord injury (SCI) may experience several types of chronic pain, including
peripheral and central neuropathic pain, pain secondary to overuse, painful muscle spasms …
peripheral and central neuropathic pain, pain secondary to overuse, painful muscle spasms …
Acupuncture‐Analgesia‐Mediated Alleviation of Central Sensitization
HC Lai, YW Lin, CL Hsieh - Evidence‐Based Complementary …, 2019 - Wiley Online Library
Pain can trigger central amplification called central sensitization, which ultimately results in
hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic …
hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic …
The role of microstructured and interconnected pore channels in a collagen-based nerve guide on axonal regeneration in peripheral nerves
A Bozkurt, F Lassner, D O'Dey, R Deumens, A Böcker… - Biomaterials, 2012 - Elsevier
The use of bioengineered nerve guides as alternatives for autologous nerve transplantation
(ANT) is a promising strategy for the repair of peripheral nerve defects. In the present …
(ANT) is a promising strategy for the repair of peripheral nerve defects. In the present …
Prevention of chronic postoperative pain: cellular, molecular, and clinical insights for mechanism-based treatment approaches
Nearly every surgery can elicit a rather therapy-resistant chronic postoperative pain.
Preventive medicine is therefore anticipated with hopeful eyes, but requires a better …
Preventive medicine is therefore anticipated with hopeful eyes, but requires a better …
Injectable alginate hydrogel loaded with GDNF promotes functional recovery in a hemisection model of spinal cord injury
E Ansorena, P De Berdt, B Ucakar… - International journal of …, 2013 - Elsevier
We hypothesized that local delivery of GDNF in spinal cord lesion via an injectable alginate
hydrogel gelifying in situ would support spinal cord plasticity and functional recovery. The …
hydrogel gelifying in situ would support spinal cord plasticity and functional recovery. The …
Local knockdown of the NaV1. 6 sodium channel reduces pain behaviors, sensory neuron excitability, and sympathetic sprouting in rat models of neuropathic pain
In the spinal nerve ligation (SNL) model of neuropathic pain, as in other pain models,
abnormal spontaneous activity of myelinated sensory neurons occurs early and is essential …
abnormal spontaneous activity of myelinated sensory neurons occurs early and is essential …