[HTML][HTML] Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical Society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

[HTML][HTML] Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

T Bieber - Nature reviews Drug discovery, 2022 - nature.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …

Skin cancer detection: a review using deep learning techniques

M Dildar, S Akram, M Irfan, HU Khan… - International journal of …, 2021 - mdpi.com
Skin cancer is one of the most dangerous forms of cancer. Skin cancer is caused by un-
repaired deoxyribonucleic acid (DNA) in skin cells, which generate genetic defects or …

Hyaluronic acid—Based wound dressings: A review

MFP Graça, SP Miguel, CSD Cabral, IJ Correia - Carbohydrate polymers, 2020 - Elsevier
Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of
skin extracellular matrix (ECM) and it is involved in the inflammatory response …

Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

T Nakatsuji, TR Hata, Y Tong, JY Cheng, F Shafiq… - Nature medicine, 2021 - nature.com
Staphylococcus aureus colonizes patients with atopic dermatitis (AD) and exacerbates
disease by promoting inflammation. The present study investigated the safety and …

Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

[HTML][HTML] Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Psoriasis pathogenesis and treatment

A Rendon, K Schäkel - International journal of molecular sciences, 2019 - mdpi.com
Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

MAIT cells are imprinted by the microbiota in early life and promote tissue repair

MG Constantinides, VM Link, S Tamoutounour… - Science, 2019 - science.org
INTRODUCTION The microbiota promotes the maturation and homeostasis of the immune
system, in part through the release of microbial products. Early-life microbial colonization …