A necroptosis-related gene signature to predict prognosis and immune features in hepatocellular carcinoma

K Zhang, J Li, E Yuan - BMC cancer, 2023 - Springer
Abstract Background and Aim Necroptosis plays an important role in hepatocellular
carcinoma (HCC) development, recurrence, and immunotherapy tolerance. We aimed to …

[HTML][HTML] Calycosin pretreatment enhanced the therapeutic efficacy of mesenchymal stem cells to alleviate unilateral ureteral obstruction-induced renal fibrosis by …

Q Hu, B Zhu, G Yang, J Jia, H Wang, R Tan… - Journal of …, 2023 - Elsevier
Bone marrow-derived mesenchymal stem cells (MSCs) show antifibrotic activity in various
chronic kidney diseases. Here, we aimed to investigate whether Calycosin (CA), a …

Buffalo milk whey activates necroptosis and apoptosis in a xenograft model of colorectal cancer

NA Cacciola, A Salzano, N D'Onofrio… - International Journal of …, 2022 - mdpi.com
Recent pharmacological research on milk whey, a byproduct of the dairy industry, has
identified several therapeutic properties that could be exploited in modern medicine. In the …

Exosomes treating osteoarthritis: hope with challenge

C Wu, Y He, Y Yao, H Yang, F Lu - Heliyon, 2023 - cell.com
Osteoarthritis (OA) has been proven as the second primary cause of pain and disability in
the elderly population, impact patients both physically and mentally, as well as imposing a …

Programmed cell death in tumor immunity: mechanistic insights and clinical implications

M Wang, F Yu, Y Zhang, P Li - Frontiers in Immunology, 2024 - frontiersin.org
Programmed cell death (PCD) is an evolutionarily conserved mechanism of cell suicide that
is controlled by various signaling pathways. PCD plays an important role in a multitude of …

[HTML][HTML] Magnolia officinalis bark extract improves depressive-like behavior in DSS-induced colitis mice

MS Kim, J Kim, KI Lee, HJ Kim, H Kim, D Kim… - Journal of Functional …, 2023 - Elsevier
Most studies on the pathogenesis of inflammatory bowel disease (IBD) focus on gut function
damage and gastrointestinal symptoms; however, psychiatric disorders, including …

A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases

X Shen, H Chen, T Wen, L Liu, Y Yang, F Xie… - European Journal of …, 2023 - Elsevier
Necroptosis, a new form of programmed cell death, is involved in the pathogenesis of
ulcerative colitis (UC). Inhibition of necroptosis represents an attractive strategy for UC …

Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis

SM Bozonet, NJ Magon, AJ Schwartfeger… - Journal of Biological …, 2023 - ASBMB
Necroptosis is a form of regulated cell death triggered by various host and pathogen-derived
molecules during infection and inflammation. The essential step leading to necroptosis is …

Necroptosis in human cancers with special emphasis on oral squamous cell carcinoma

RP Krishnan, D Pandiar, P Ramani… - Journal of Stomatology …, 2023 - Elsevier
Necroptosis is a type of caspase independent 'programmed or regulated'necrotic cell death
that has a morphological resemblance to necrosis and mechanistic analogy to apoptosis …

Anticancer potential and through study of the cytotoxicity mechanism of ionic liquids that are based on the trifluoromethanesulfonate and bis (trifluoromethylsulfonyl) …

M Kuczak, M Musiał, K Malarz, P Rurka… - Journal of Hazardous …, 2022 - Elsevier
Ionic liquids (ILs) are known for their unique physicochemical properties. However, despite
the great number of published papers, still little attention has been paid to their biological …