Background: Diabetic nephropathy (DN) was considered a severe microvascular
complication of diabetes, which was recognized as the second leading cause of end-stage …

Background Studies have found that the plasma content of gut-derived 4-
hydroxyphenylacetic acid (4-HPA) was significantly increased in septic patients. However …

Background. Bladder cancer (BC) is one of the most serious genitourinary malignant
diseases with a poor prognosis. Necroptosis is a regulated form of cell death, and targeting …

Abstract Eight undescribed (1–8) and 46 known compounds (9–54) were isolated from the
deep-sea-derived Aspergillus sp. MCCC 3A00392. Compounds 1–3 were three novel …

Abstract Coronavirus disease 2019 (Covid‐19) is an emerging novel respiratory infectious
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) that …

Necroptosis is a pivotal contributor to the pathogenesis of various human diseases,
including those affecting the nervous system, cardiovascular system, pulmonary system, and …

Background: The mutual activation between nucleus pulposus (NP) cells death and
inflammation is an important pathogenic factor of intervertebral disc degeneration. Whether …

Quercetin (Que) is a flavonol compound found in plants, which has a variety of biological
activities. Necroptosis, a special form of programmed cell death, plays a vital role in the …

Inherited retinal diseases (IRDs) are a leading cause of blindness. To date, 260 disease-
causing genes have been identified, but there is currently a lack of available and effective …

Cerebral cortex projection neurons (PNs) are generated from intermediate progenitors (IPs),
which are in turn derived from radial glial progenitors (RGPs). To investigate developmental …