Background: A growing proportion of patients on antiretroviral therapy in resource-limited
settings have switched to second-line regimens. We carried out a systematic review in order …

Introduction Antiretroviral therapy (ART) in resource-limited settings has expanded in the last
decade, reaching> 8 million individuals and reducing AIDS mortality and morbidity …

Objectives: To measure rates and predictors of virologic failure and switch to second-line
antiretroviral therapy (ART) in South Africa. Design: Observational cohort study. Methods …

Abstract Background In sub-Saharan Africa, 25.5 million people are living with human
immunodeficiency virus (HIV), representing 70% of the global total. The need for second-line …

Objective In resource‐limited settings, where genotypic drug resistance testing is rarely
performed and poor adherence is the most common reason for treatment failure …

Background: The World Health Organization recommends that antiretroviral therapy (ART)
programs in resource-limited settings develop third-line ART policies. South Africa …

Objectives South Africa's national antiretroviral (ARV) treatment program expanded in 2010
to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for …

Abstract Imidazolidinones and imidazolidine‐2, 4‐diones are important classes of
heterocyclic compounds that possess potent activities against several viruses such as …

Introduction: The number of HIV‐infected children and adolescents requiring second‐line
antiretroviral treatment (ART) is increasing in low‐and middle‐income countries (LMIC) …

Background We investigated the prevalence of wild-type virus (no major drug resistance)
and drug resistance mutations at second-line antiretroviral treatment (ART) failure in a large …