BACKGROUND: Diabetes mellitus (DM), chronic disease, is a public health problem that
affects 8.5% adult population worldwide. The number of adults with DM has risen sharply …

Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …

Background Coronary artery disease (CAD) is the leading cause of death in the United
States (US) and a major contributor to healthcare cost. Accurate segmentation of coronary …

Background Diabetes mellitus (DM) and coronary artery disease (CAD) constitute inter-
related clinical entities. Biomarker profiling emerges as a promising tool for the early …

Both acute and prolonged cold exposure affect cardiovascular responses, which may be
modified by an underlying cardiovascular disease. In addition, exercise in a cold …

Diabetic cardiomyopathy is one of the main causes of heart failure and death in patients with
diabetes mellitus. Reactive oxygen species produced excessively in diabetes mellitus cause …

Background Several studies have demonstrated that coronary heart disease (CHD) is a high
risk factor for cognitive impairment, whereas other studies showed that there was no …

The aryl hydrocarbon receptor (AhR) is a DNA binding protein that acts as a nuclear
receptor mediating xenobiotic metabolism and environmental responses. Owing to the …

Abstract Hypoxia-inducible factors (HIF)-1 and HIF-2 are master regulators of oxygen
homeostasis that regulate the expression of thousands of genes in order to match O2 supply …

Abstract Purpose of Review Persons with diabetes mellitus (DM) have increased morbidity
and mortality rates compared with persons without DM. Sudden cardiac death (SCD) is a …