Once relegated to investigational or ancillary roles, nucleic acid-based molecular tests have
become essential for the diagnosis and management of most hematologic malignancies …

Background Myelodysplastic syndromes (MDSs) are a very heterogeneous group of myeloid
disorders with high prevalence and risk of developing acute myeloid leukemia. The more …

Myelodysplastic neoplasm (MDS) is a heterogeneous group of myeloid neoplasms affected
by germline and somatic genetic alterations. The incidence of MDS increases with age but …

Background Splicing modifications, genomic instability, and hypomethylation are central
mechanisms promoting myelodysplasia and acute myeloid leukemia (AML). In this real‐life …

Gene mutations play a crucial role in the pathogenesis of myelodysplastic neoplasms
(MDS). The present study aimed to assess the association between some gene mutations …

Platelets (PLTs) are believed to play a role in the process by which tumors can accelerate
their growth rate, as well as offer the physical and mechanical support necessary to evade …

Background: Somatic mutations are widespread in patients with Myelodysplastic Syndrome
(MDS) and are associated with prognosis. However, a practical prognostic model for MDS …

Myelodysplastic syndromes (MDS) are clonal stem cell disorders characterized by
ineffective hematopoiesis with varying degrees of dysplasia and peripheral cytopenias. 1 …

Myelodysplastic syndromes (MDS) are clonal stem cells disorders characterized by
ineffective hematopoiesis with varying degrees of dysplasia and peripheral cytopenias (1) …

Leukemias, lymphomas, plasma cell disorders, and related neoplasms are hematologic
malignancies characterized by various recurrent acquired genetic and genomic …