The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

Although influenza is a major public health concern, little is known about the use of spray
live attenuated influenza vaccine (LAIV) among adults. For this reason, we conducted a …

A newly identified coronavirus, named SARS-CoV-2, emerged in December 2019 in Hubei
Province, China, and quickly spread throughout the world; so far, it has caused more than …

Antibody responses to influenza virus hemagglutinin provide protection against infection
and are well studied. Less is known about the human antibody responses to the second …

Background. The recently emerged SARS‐CoV‐2 Omicron variant exhibits several
mutations on the spike protein, enabling it to escape the immunity elicited by natural …

The constant domains of antibodies are important for effector functions, but less is known
about how they can affect binding and neutralization of viruses. Here, we evaluated a panel …

Objectives Influenza causes significant morbidity and mortality, especially in high‐risk
populations. Although current vaccination regimens are the best method to combat annual …

Recent advances in high-throughput single cell sequencing have opened up new avenues
into the investigation of B cell receptor (BCR) repertoires. In this study, PBMCs were …

Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and
mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial …

Mucosal immunity has regained its spotlight amidst the ongoing Coronavirus Disease 19
(COVID-19) pandemic, with numerous studies highlighting the crucial role of mucosal …