Spine dynamics in the brain, mental disorders and artificial neural networks
In the brain, most synapses are formed on minute protrusions known as dendritic spines.
Unlike their artificial intelligence counterparts, spines are not merely tuneable memory …
Unlike their artificial intelligence counterparts, spines are not merely tuneable memory …
Mesoaccumbal dopamine heterogeneity: what do dopamine firing and release have to do with it?
Ventral tegmental area (VTA) dopamine (DA) neurons are often thought to uniformly encode
reward prediction errors. Conversely, DA release in the nucleus accumbens (NAc), the …
reward prediction errors. Conversely, DA release in the nucleus accumbens (NAc), the …
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement
The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus
accumbens (NAc) is relatively understudied, and therefore its role in reward processing has …
accumbens (NAc) is relatively understudied, and therefore its role in reward processing has …
Overlapping representations of food and social stimuli in mouse VTA dopamine neurons
Dopamine neurons of the ventral tegmental area (VTA DA) respond to food and social
stimuli and contribute to both forms of motivation. However, it is unclear whether the same or …
stimuli and contribute to both forms of motivation. However, it is unclear whether the same or …
Dopamine circuit mechanisms of addiction-like behaviors
CL Poisson, L Engel, BT Saunders - Frontiers in Neural Circuits, 2021 - frontiersin.org
Addiction is a complex disease that impacts millions of people around the world. Clinically,
addiction is formalized as substance use disorder (SUD), with three primary symptom …
addiction is formalized as substance use disorder (SUD), with three primary symptom …
Unraveling the dynamics of dopamine release and its actions on target cells
T Sippy, NX Tritsch - Trends in neurosciences, 2023 - cell.com
The neuromodulator dopamine (DA) is essential for regulating learning, motivation, and
movement. Despite its importance, however, the mechanisms by which DA influences the …
movement. Despite its importance, however, the mechanisms by which DA influences the …
A mosaic of cost–benefit control over cortico-striatal circuitry
Dopamine contributes to cognitive control through well-established effects in both the
striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …
striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …
Mesocorticolimbic dopamine pathways across adolescence: diversity in development
LM Reynolds, C Flores - Frontiers in Neural Circuits, 2021 - frontiersin.org
Mesocorticolimbic dopamine circuity undergoes a protracted maturation during adolescent
life. Stable adult levels of behavioral functioning in reward, motivational, and cognitive …
life. Stable adult levels of behavioral functioning in reward, motivational, and cognitive …
A feature-specific prediction error model explains dopaminergic heterogeneity
The hypothesis that midbrain dopamine (DA) neurons broadcast a reward prediction error
(RPE) is among the great successes of computational neuroscience. However, recent …
(RPE) is among the great successes of computational neuroscience. However, recent …
Integrating the roles of midbrain dopamine circuits in behavior and neuropsychiatric disease
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS
function. DA plays major roles in many behaviors including locomotion, learning, habit …
function. DA plays major roles in many behaviors including locomotion, learning, habit …