[HTML][HTML] Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells

L Lugini, M Valtieri, C Federici, S Cecchetti… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background Cancer cells, including colorectal cancer ones (CRC), release high amounts of
nanovesicles (exosomes), delivering biochemical messages for paracrine or systemic …

[HTML][HTML] Exosomes in mesenchymal stem cells, a new therapeutic strategy for cardiovascular diseases?

L Huang, W Ma, Y Ma, D Feng, H Chen… - International journal of …, 2015 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) are still a major cause of people deaths worldwide, and
mesenchymal stem cells (MSCs) transplantation holds great promise due to its capacity to …

Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model

M Yousefifard, F Nasirinezhad… - Stem cell research & …, 2016 - Springer
Background Stem cell therapy can be used for alleviating the neuropathic pain induced by
spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their …

Mesenchymal stem cell secretome and regenerative therapy after cancer

L Zimmerlin, TS Park, ET Zambidis, VS Donnenberg… - Biochimie, 2013 - Elsevier
Cancer treatment generally relies on tumor ablative techniques that can lead to major
functional or disfiguring defects. These post-therapy impairments require the development of …

IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells

G Di, Y Liu, Y Lu, J Liu, C Wu, HF Duan - PloS one, 2014 - journals.plos.org
Human mesenchymal stem cells (hMSCs) are currently investigated for a variety of
therapeutic applications. However, MSCs isolated from primary tissue cannot meet clinical …

Mesenchymal stem cells beyond regenerative medicine

R Shammaa, AEH El-Kadiry, J Abusarah… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are competent suitors of cellular therapy due to their
therapeutic impact on tissue degeneration and immune-based pathologies. Additionally …

Antiproliferative effects of local anesthetics on mesenchymal stem cells: potential implications for tumor spreading and wound healing

E Lucchinetti, AE Awad, M Rahman, J Feng… - The Journal of the …, 2012 - pubs.asahq.org
Background Mesenchymal stem cells (MSC) are self-renewing clonal progenitor cells of
nonhematopoietic tissues that exhibit a marked tropism to wounds and tumors. The authors' …

MSCs inhibit tumor progression and enhance radiosensitivity of breast cancer cells by down-regulating Stat3 signaling pathway

N He, Y Kong, X Lei, Y Liu, J Wang, C Xu, Y Wang… - Cell death & …, 2018 - nature.com
The acquisition of radioresistance by breast cancer cells during radiotherapy may lead to
cancer recurrence and poor survival. Signal transducer and activator of transcription 3 …

Mesenchymal stem cells as a double-edged sword in tumor growth: focusing on MSC-derived cytokines

W Liang, X Chen, S Zhang, J Fang, M Chen… - Cellular & Molecular …, 2021 - Springer
Mesenchymal stem cells (MSCs) show homing capacity towards tumor sites. Numerous
reports indicate that they are involved in multiple tumor-promoting processes through …

Advances in chemokine signaling pathways as therapeutic targets in glioblastoma

RM Urbantat, P Vajkoczy, S Brandenburg - Cancers, 2021 - mdpi.com
Simple Summary Chemokine signaling is crucial for tumorigenesis, proliferation,
angiogenesis, tumor progression and metastasis in glioblastoma. Furthermore, chemokines …