Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

Cardiovascular disease is the main disease that affects human life span. In recent years, the
disease has been increasingly addressed at the molecular levels, for example …

Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal
stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal …

Background Hypertrophy of ligamentum flavum (HLF) is a common lumbar degeneration
disease (LDD) with typical symptoms of low back pain and limb numbness owing to an …

Epigenetic modifications, particularly DNA methylation, have emerged as regulators of gene
expression and are implicated in various biological processes and disease states …

AFG3L2 is a zinc metalloprotease and an ATPase localized in an inner mitochondrial
membrane involved in mitochondrial quality control of several nuclear-and mitochondrial …

AFG3L2 is a zinc metalloprotease and an ATPase localized in an inner mitochondrial
membrane involved in mitochondrial quality control of several nuclear-and mitochondrial …

Myocardial infarction (MI) is a complicated pathology triggered by numerous environmental
and genetic factors. Understanding the effect of epigenetic regulation mechanisms on the …

Introduction Van der Woude Syndrome (VWS) is an autosomal dominant disorder
responsible for 2% of all syndromic orofacial clefts (OFCs) with IRF6 being the primary …

As many authors state, aging has been conceptualized as a biological process that leads to
declining function and increases the susceptibility to age-related diseases such as cancer …