IL-17A is a therapeutic target in many autoimmune diseases. Most nonhematopoietic cells
express IL-17A receptors and respond to extracellular IL-17A by inducing proinflammatory …

BACKGROUND Probiotics regulate host immune balance, which may reduce immune‐
related diseases. The effects and mechanisms of Lactobacillus rhamnosus 2016SWU …

Immune cells and cytokines play an important role in the pathogenesis of psoriasis.
Interleukin‐12 (IL‐12) and IL‐23 promote cellular responses mediated by T cells, which …

Interleukin-23 (IL-23) is a proinflammatory cytokine initially studied in autoimmune disease
that has been more recently linked to innate immunity. We observed that the expression of IL …

Background The cytokine IL-17 is a key player in autoimmune processes, while the cytokine
IL-6 is responsible for the chronification of inflammation. However, their roles in type 1 …

Bmi1 is a polycomb group protein and regulator that stabilizes the ubiquitination complex
PRC1 in the nucleus with no evidently direct link to the NF-κB pathway. In this study, we …

В последние годы большое внимание привлекают ТҺ17-клетки, патологическая
активация которых играет ведущую роль в развитии широкого спектра …

The history of psoriasis treatment has been marked by several milestones. Corticosteroids,
cyclosporine, tumor necrosis factor alpha (TNF-α) inhibitors and, more recently, interleukin …

There is limited evidence on the effects of environmental exposure to arsenic (As) on the
immune system in adults. In a population-based study, we have found that urinary As (UAs) …

Background and Purpose Psoriasis is a chronic immune‐mediated inflammatory skin
disease that easily recurs and is difficult to cure. DGT is a novel synthetic heterocyclic …