The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Bone is an alive and dynamic organ that is well-differentiated and originated from
mesenchymal tissues. Bone undergoes continuous remodeling during the lifetime of an …

Background In recent years, there has been significant research progress on in situ articular
cartilage (AC) tissue engineering with endogenous stem cells, which uses biological …

Osteoarthritis (OA) is increasing in prevalence and has a severe impact on patients' lives.
However, our understanding of biomarkers driving OA risk remains limited. We developed a …

Objective To examine the genetic architecture of cam morphology using alpha angle (AA) as
a proxy measure and conduct an AA genome‐wide association study (GWAS) followed by …

Osteoarthritis is a complex degenerative disease that affects the entire joint tissue. Currently,
non-surgical treatments for osteoarthritis focus on relieving pain. While end-stage …

Background Osteoarthritis (OA) is a common degenerative joint disease and causes chronic
pain and disability to the elderly. Several risk factors are involved, such as aging, obesity …

Background Hoof structure and health are essential for the welfare and productivity of beef
cattle. Therefore, we assessed the genetic and genomic background of foot score traits in …

Osteoarthritis (OA) is the most prevalent disorder of synovial joint affecting multiple joints. In
the past decade, we have witnessed conceptual switch of OA pathogenesis from a 'wear and …

Intervertebral disc (IVD) degeneration (IVDD) has been considered the dominant factor in
low back pain (LBP), and its etiological mechanisms are complex and not yet fully …