Endogenous pain regulatory system dysfunction appears to play a role in the maintenance
of chronic pain. An important component of the pain regulatory process is the functional …

Until relatively recently, depression has been considered a purely “mental” disorder and
therefore in the natural domain of psychologists and psychiatrists. However, recent …

The association between the clinical use of nitroglycerin (NTG) and headache has led to the
examination of NTG as a model trigger for migraine and related headache disorders, both in …

Contrasting findings on the mechanisms of chronic pain and hypertension development
render the current conventional evidence of a negative relationship between blood pressure …

Evidence indicates that genetic, gender, and emotional/attentional aspects modulate the
pain sensation. The present study examined the effect of swim-stress on nociceptive …

Altered pain responding in depression is a widely recognized but poorly understood
phenomenon. The present study investigated nociceptive responding to acute (thermal and …

Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present
abnormalities in emotion processing. A previous study showed that the spontaneously …

Background Hypertension is a common comorbidity of osteoarthritis (OA) with known
autonomic dysregulation; thus, the autonomic nervous system may provide a shared …

Pain is both a sensory and an emotional experience, and is subject to modulation by a
number of factors including genetic background modulating stress/affect. The Wistar–Kyoto …

Studies suggest that the endocannabinoid and endovanilloid systems are implicated in the
pathophysiology of schizophrenia. The Spontaneously Hypertensive Rats (SHR) strain …