Stroke is a leading cause of disability and mortality, with limited treatment options. After
stroke injury, microglia and CNS‐resident macrophages are rapidly activated and regulate …

Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Accumulating evidence have indicated that ferroptosis plays a crucial role in cerebral
ischemia-reperfusion (I/R) injury which is the most serious treatment complication of …

Background: There are no evidence-based recommendations on the optimal time point to
initiate non–vitamin K antagonist oral anticoagulants (NOACs) after acute ischemic stroke in …

The 2017 update of The Canadian Stroke Best Practice Recommendations for the
Secondary Prevention of Stroke is a collection of current evidence-based recommendations …

Executive summary Stroke is the second leading cause of death worldwide. The burden of
disability after a stroke is also large, and is increasing at a faster pace in low-income and …

Background People with stroke or transient ischaemic attack (TIA) are at increased risk of
future stroke and other cardiovascular events. Stroke services need to be configured to …

Background The underlying etiology of ischemic stroke remains unknown in up to 30% of
patients. Objectives This study explored the causal role of complicated (American Heart …

Background and Purpose—Previous studies have shown heterogeneous results on
predictors and rates of stroke recurrence. This study set out to investigate the long-term risk …

Background: Despite improvements in diagnostic and therapeutic interventions to combat
cardiovascular disease (CVD) in recent decades, there are significant ongoing access gaps …